TFKLL_HUMAN
ID TFKLL_HUMAN Reviewed; 197 AA.
AC A0A1W2PPW3;
DT 03-AUG-2022, integrated into UniProtKB/Swiss-Prot.
DT 07-JUN-2017, sequence version 1.
DT 03-AUG-2022, entry version 23.
DE RecName: Full=TATA-box-binding protein-associated factor 11-like protein 12 {ECO:0000305};
GN Name=TAF11L12 {ECO:0000312|HGNC:HGNC:53855};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15372022; DOI=10.1038/nature02919;
RA Schmutz J., Martin J., Terry A., Couronne O., Grimwood J., Lowry S.,
RA Gordon L.A., Scott D., Xie G., Huang W., Hellsten U., Tran-Gyamfi M.,
RA She X., Prabhakar S., Aerts A., Altherr M., Bajorek E., Black S.,
RA Branscomb E., Caoile C., Challacombe J.F., Chan Y.M., Denys M.,
RA Detter J.C., Escobar J., Flowers D., Fotopulos D., Glavina T., Gomez M.,
RA Gonzales E., Goodstein D., Grigoriev I., Groza M., Hammon N., Hawkins T.,
RA Haydu L., Israni S., Jett J., Kadner K., Kimball H., Kobayashi A.,
RA Lopez F., Lou Y., Martinez D., Medina C., Morgan J., Nandkeshwar R.,
RA Noonan J.P., Pitluck S., Pollard M., Predki P., Priest J., Ramirez L.,
RA Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A., Thayer N.,
RA Tice H., Tsai M., Ustaszewska A., Vo N., Wheeler J., Wu K., Yang J.,
RA Dickson M., Cheng J.-F., Eichler E.E., Olsen A., Pennacchio L.A.,
RA Rokhsar D.S., Richardson P., Lucas S.M., Myers R.M., Rubin E.M.;
RT "The DNA sequence and comparative analysis of human chromosome 5.";
RL Nature 431:268-274(2004).
RN [2]
RP TISSUE SPECIFICITY.
RX PubMed=21078170; DOI=10.1186/1471-2164-11-632;
RA Tremblay D.C., Alexander G. Jr., Moseley S., Chadwick B.P.;
RT "Expression, tandem repeat copy number variation and stability of four
RT macrosatellite arrays in the human genome.";
RL BMC Genomics 11:632-632(2010).
CC -!- TISSUE SPECIFICITY: Expressed in fetal brain and testis.
CC {ECO:0000269|PubMed:21078170}.
CC -!- SIMILARITY: Belongs to the TAF11 family. {ECO:0000305}.
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DR EMBL; AC233724; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR SMR; A0A1W2PPW3; -.
DR BioMuta; ENSG00000249156; -.
DR Ensembl; ENST00000503184; ENSP00000491758; ENSG00000249156.
DR GeneCards; TAF11L12; -.
DR HGNC; HGNC:53855; TAF11L12.
DR VEuPathDB; HostDB:ENSG00000249156; -.
DR GeneTree; ENSGT00390000013228; -.
DR OMA; DITEMFI; -.
DR Proteomes; UP000005640; Chromosome 5.
DR RNAct; A0A1W2PPW3; protein.
DR Bgee; ENSG00000249156; Expressed in blood and 6 other tissues.
DR GO; GO:0005669; C:transcription factor TFIID complex; IBA:GO_Central.
DR GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro.
DR GO; GO:0003713; F:transcription coactivator activity; IBA:GO_Central.
DR GO; GO:0051123; P:RNA polymerase II preinitiation complex assembly; IBA:GO_Central.
DR CDD; cd08048; TAF11; 1.
DR Gene3D; 1.10.20.10; -; 1.
DR InterPro; IPR009072; Histone-fold.
DR InterPro; IPR045127; TAF11-like.
DR InterPro; IPR006809; TAFII28_dom.
DR PANTHER; PTHR13218; PTHR13218; 1.
DR Pfam; PF04719; TAFII28; 1.
DR SUPFAM; SSF47113; SSF47113; 1.
PE 2: Evidence at transcript level;
KW Reference proteome.
FT CHAIN 1..197
FT /note="TATA-box-binding protein-associated factor 11-like
FT protein 12"
FT /id="PRO_0000456152"
SQ SEQUENCE 197 AA; 21787 MW; 3201AB36BF5A2964 CRC64;
METGRQRGAS AEMFAMPQGL KGSNKDGIPE DLDGNLEEPR DQESELRSQD VMDLTEGDNE
ASASAPPAAK RQKTDTKGKK ERKPTVDAEE AQMTTLLYAM SEEQLSRYEV CRRSAFPKAR
IAALMQSITG RSVSENTAIA MAGIAKVLVG EVVEEALDVC EMWGETPPLQ PKHLREAVRR
LKPKGLFPNS NYKKIMF
