TFKLN_HUMAN
ID TFKLN_HUMAN Reviewed; 197 AA.
AC A0A1W2PPL8;
DT 03-AUG-2022, integrated into UniProtKB/Swiss-Prot.
DT 07-JUN-2017, sequence version 1.
DT 03-AUG-2022, entry version 22.
DE RecName: Full=TATA-box-binding protein-associated factor 11-like protein 14 {ECO:0000305};
GN Name=TAF11L14 {ECO:0000312|HGNC:HGNC:53857};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15372022; DOI=10.1038/nature02919;
RA Schmutz J., Martin J., Terry A., Couronne O., Grimwood J., Lowry S.,
RA Gordon L.A., Scott D., Xie G., Huang W., Hellsten U., Tran-Gyamfi M.,
RA She X., Prabhakar S., Aerts A., Altherr M., Bajorek E., Black S.,
RA Branscomb E., Caoile C., Challacombe J.F., Chan Y.M., Denys M.,
RA Detter J.C., Escobar J., Flowers D., Fotopulos D., Glavina T., Gomez M.,
RA Gonzales E., Goodstein D., Grigoriev I., Groza M., Hammon N., Hawkins T.,
RA Haydu L., Israni S., Jett J., Kadner K., Kimball H., Kobayashi A.,
RA Lopez F., Lou Y., Martinez D., Medina C., Morgan J., Nandkeshwar R.,
RA Noonan J.P., Pitluck S., Pollard M., Predki P., Priest J., Ramirez L.,
RA Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A., Thayer N.,
RA Tice H., Tsai M., Ustaszewska A., Vo N., Wheeler J., Wu K., Yang J.,
RA Dickson M., Cheng J.-F., Eichler E.E., Olsen A., Pennacchio L.A.,
RA Rokhsar D.S., Richardson P., Lucas S.M., Myers R.M., Rubin E.M.;
RT "The DNA sequence and comparative analysis of human chromosome 5.";
RL Nature 431:268-274(2004).
RN [2]
RP TISSUE SPECIFICITY.
RX PubMed=21078170; DOI=10.1186/1471-2164-11-632;
RA Tremblay D.C., Alexander G. Jr., Moseley S., Chadwick B.P.;
RT "Expression, tandem repeat copy number variation and stability of four
RT macrosatellite arrays in the human genome.";
RL BMC Genomics 11:632-632(2010).
CC -!- TISSUE SPECIFICITY: Expressed in fetal brain and testis.
CC {ECO:0000269|PubMed:21078170}.
CC -!- SIMILARITY: Belongs to the TAF11 family. {ECO:0000305}.
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DR EMBL; AC233724; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR SMR; A0A1W2PPL8; -.
DR BioMuta; ENSG00000250782; -.
DR PeptideAtlas; A0A1W2PPL8; -.
DR Ensembl; ENST00000512227; ENSP00000491472; ENSG00000250782.
DR GeneCards; TAF11L14; -.
DR HGNC; HGNC:53857; TAF11L14.
DR VEuPathDB; HostDB:ENSG00000250782; -.
DR GeneTree; ENSGT00390000013228; -.
DR OMA; ENMAIAM; -.
DR Proteomes; UP000005640; Chromosome 5.
DR RNAct; A0A1W2PPL8; protein.
DR Bgee; ENSG00000250782; Expressed in hindlimb stylopod muscle and 7 other tissues.
DR GO; GO:0005669; C:transcription factor TFIID complex; IBA:GO_Central.
DR GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro.
DR GO; GO:0003713; F:transcription coactivator activity; IBA:GO_Central.
DR GO; GO:0051123; P:RNA polymerase II preinitiation complex assembly; IBA:GO_Central.
DR CDD; cd08048; TAF11; 1.
DR Gene3D; 1.10.20.10; -; 1.
DR InterPro; IPR009072; Histone-fold.
DR InterPro; IPR045127; TAF11-like.
DR InterPro; IPR006809; TAFII28_dom.
DR PANTHER; PTHR13218; PTHR13218; 1.
DR Pfam; PF04719; TAFII28; 1.
DR SUPFAM; SSF47113; SSF47113; 1.
PE 2: Evidence at transcript level;
KW Reference proteome.
FT CHAIN 1..197
FT /note="TATA-box-binding protein-associated factor 11-like
FT protein 14"
FT /id="PRO_0000456154"
SQ SEQUENCE 197 AA; 21841 MW; C22FBB4B8537F872 CRC64;
METGRQTGVS AEMFAIPRGL KGCNEDGIPE ALDGNLEEPR AQECELRSED VMDLTVVDNE
ASASAPPAAK RQKTDTKGQK ERKPSVDAEE AQRMTTLLSA MSEEQLSRYE VCRQLAFPKA
LVARLMWSIT GRSVPENMAI AMAGIAKVFV GEVVEEALDM CEMWGEMPPL QPMDLREAVC
RLKPKGLFPN NYKKVMF