ID   TF_NEOBT                Reviewed;         425 AA.
AC   Q6F5E1;
DT   30-NOV-2016, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   25-MAY-2022, entry version 56.
DE   RecName: Full=Aspyridones cluster regulator {ECO:0000303|PubMed:14745177};
GN   Name=TF;
OS   Neocamarosporium betae (Beet black rot fungus) (Pleospora betae).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC   Pleosporomycetidae; Pleosporales; Pleosporineae; Pleosporaceae;
OC   Neocamarosporium.
OX   NCBI_TaxID=1979465;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND IDENTIFICATION OF GENE CLUSTER.
RC   STRAIN=PS-16;
RX   PubMed=14745177; DOI=10.1271/bbb.68.146;
RA   Toyomasu T., Nakaminami K., Toshima H., Mie T., Watanabe K., Ito H.,
RA   Matsui H., Mitsuhashi W., Sassa T., Oikawa H.;
RT   "Cloning of a gene cluster responsible for the biosynthesis of diterpene
RT   aphidicolin, a specific inhibitor of DNA polymerase alpha.";
RL   Biosci. Biotechnol. Biochem. 68:146-152(2004).
CC   -!- FUNCTION: Transcription factor involved in regulation of gene cluster
CC       that mediates the biosynthesis of aphidicolin (PubMed:14745177).
CC       {ECO:0000305|PubMed:14745177}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00227}.
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DR   EMBL; AB114137; BAD29975.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q6F5E1; -.
DR   SMR; Q6F5E1; -.
DR   PRIDE; Q6F5E1; -.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0045122; P:aflatoxin biosynthetic process; IEA:InterPro.
DR   CDD; cd00067; GAL4; 1.
DR   Gene3D; 4.10.240.10; -; 1.
DR   InterPro; IPR013700; AflR.
DR   InterPro; IPR001138; Zn2-C6_fun-type_DNA-bd.
DR   InterPro; IPR036864; Zn2-C6_fun-type_DNA-bd_sf.
DR   Pfam; PF08493; AflR; 1.
DR   SUPFAM; SSF57701; SSF57701; 1.
DR   PROSITE; PS00463; ZN2_CY6_FUNGAL_1; 1.
DR   PROSITE; PS50048; ZN2_CY6_FUNGAL_2; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Metal-binding; Nucleus; Transcription;
KW   Transcription regulation; Zinc.
FT   CHAIN           1..425
FT                   /note="Aspyridones cluster regulator"
FT                   /id="PRO_0000438561"
FT   DNA_BIND        100..127
FT                   /note="Zn(2)-C6 fungal-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00227"
FT   REGION          132..159
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   425 AA;  47237 MW;  6C896DF598B1CBCE CRC64;
     MTPSDICPAI ELPSSSRCMR IDYVGHPDAF SSCSNLCPTN LLRCIYSVRK YVLVRALSNF
     EDNTMFCTLR RSKDANKSYA IHMDDPPFAR TKGRLSAIAC VDCRASKTRC TGEPEGCKRC
     TFRKRPCQYP NLRRSNTTQH GEQIEASSST FTMSDEQGSL GMEVSGQGSL DAQDINFANE
     LTPVETAATM SDTMMSSECV TLNDSTITSS TIPFSIDSDI DLWNDVTGMA GSDTTSLWDY
     NAGSNDNIAA ISTKEYVCAC FAQALKTYES AEVHLVWSGR AHTADIMGLL QQQKNTISDC
     ERLLDCVQCI EKSAFVVLLI SICGKVLRSV EDASRELRPR DSVTEPTTKS KDPSQACLNI
     DANSISRHQL DDDDRLVVLG SLFLNRVTKL RSLIAAIEML VMKRNWHIQR DMVRQLKSRV
     RLIDT