ID   TG125_CAEBR             Reviewed;         368 AA.
AC   A8X8C6;
DT   04-NOV-2008, integrated into UniProtKB/Swiss-Prot.
DT   15-JAN-2008, sequence version 1.
DT   03-AUG-2022, entry version 77.
DE   RecName: Full=WD repeat-containing protein tag-125;
GN   Name=tag-125 {ECO:0000312|EMBL:CAP28887.1}; ORFNames=CBG09206;
OS   Caenorhabditis briggsae.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6238;
RN   [1] {ECO:0000312|EMBL:CAP28887.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AF16 {ECO:0000312|EMBL:CAP28887.1};
RX   PubMed=14624247; DOI=10.1371/journal.pbio.0000045;
RA   Stein L.D., Bao Z., Blasiar D., Blumenthal T., Brent M.R., Chen N.,
RA   Chinwalla A., Clarke L., Clee C., Coghlan A., Coulson A., D'Eustachio P.,
RA   Fitch D.H.A., Fulton L.A., Fulton R.E., Griffiths-Jones S., Harris T.W.,
RA   Hillier L.W., Kamath R., Kuwabara P.E., Mardis E.R., Marra M.A.,
RA   Miner T.L., Minx P., Mullikin J.C., Plumb R.W., Rogers J., Schein J.E.,
RA   Sohrmann M., Spieth J., Stajich J.E., Wei C., Willey D., Wilson R.K.,
RA   Durbin R.M., Waterston R.H.;
RT   "The genome sequence of Caenorhabditis briggsae: a platform for comparative
RT   genomics.";
RL   PLoS Biol. 1:166-192(2003).
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DR   EMBL; HE601123; CAP28887.1; -; Genomic_DNA.
DR   RefSeq; XP_002641984.1; XM_002641938.1.
DR   AlphaFoldDB; A8X8C6; -.
DR   SMR; A8X8C6; -.
DR   STRING; 6238.CBG09206; -.
DR   EnsemblMetazoa; CBG09206.1; CBG09206.1; WBGene00030836.
DR   GeneID; 8583978; -.
DR   KEGG; cbr:CBG_09206; -.
DR   CTD; 8583978; -.
DR   WormBase; CBG09206; CBP08209; WBGene00030836; -.
DR   eggNOG; KOG0266; Eukaryota.
DR   HOGENOM; CLU_000288_57_1_1; -.
DR   InParanoid; A8X8C6; -.
DR   OMA; RLWNYHT; -.
DR   OrthoDB; 957291at2759; -.
DR   Proteomes; UP000008549; Chromosome III.
DR   GO; GO:0005737; C:cytoplasm; IEA:EnsemblMetazoa.
DR   GO; GO:0044666; C:MLL3/4 complex; IEA:EnsemblMetazoa.
DR   GO; GO:0048188; C:Set1C/COMPASS complex; IBA:GO_Central.
DR   GO; GO:0042393; F:histone binding; IBA:GO_Central.
DR   GO; GO:0061629; F:RNA polymerase II-specific DNA-binding transcription factor binding; IEA:EnsemblMetazoa.
DR   GO; GO:0008340; P:determination of adult lifespan; IEA:EnsemblMetazoa.
DR   GO; GO:0051568; P:histone H3-K4 methylation; IBA:GO_Central.
DR   GO; GO:0012501; P:programmed cell death; IEA:EnsemblMetazoa.
DR   GO; GO:0060290; P:transdifferentiation; IEA:EnsemblMetazoa.
DR   Gene3D; 2.130.10.10; -; 1.
DR   InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR019775; WD40_repeat_CS.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   Pfam; PF00400; WD40; 7.
DR   PRINTS; PR00320; GPROTEINBRPT.
DR   SMART; SM00320; WD40; 7.
DR   SUPFAM; SSF50978; SSF50978; 1.
DR   PROSITE; PS00678; WD_REPEATS_1; 5.
DR   PROSITE; PS50082; WD_REPEATS_2; 6.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   4: Predicted;
KW   Reference proteome; Repeat; WD repeat.
FT   CHAIN           1..368
FT                   /note="WD repeat-containing protein tag-125"
FT                   /id="PRO_0000353202"
FT   REPEAT          77..116
FT                   /note="WD 1"
FT                   /evidence="ECO:0000255"
FT   REPEAT          119..158
FT                   /note="WD 2"
FT                   /evidence="ECO:0000255"
FT   REPEAT          161..200
FT                   /note="WD 3"
FT                   /evidence="ECO:0000255"
FT   REPEAT          203..242
FT                   /note="WD 4"
FT                   /evidence="ECO:0000255"
FT   REPEAT          246..285
FT                   /note="WD 5"
FT                   /evidence="ECO:0000255"
FT   REPEAT          288..330
FT                   /note="WD 6"
FT                   /evidence="ECO:0000255"
FT   REPEAT          333..368
FT                   /note="WD 7"
FT                   /evidence="ECO:0000255"
FT   REGION          1..64
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        41..64
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   368 AA;  39677 MW;  26E109F2E2055EFE CRC64;
     MDPAQNQPNT EPPAAPAVEE AQGVNNSEAE APAPAALSSV SPANPPITAV PEATAPTTSQ
     ESTIPGAGYK LISTIEGHTK SISAVKFSPC GKFLGTSSAD KTVKIWNMSD LSCERTLTGH
     KLGVNDFAWS ADSKSIVTAS DDKTLKIYEV PTVKMAKTLK GHTNYVFCCN FNPQSSLVVS
     GSFDESVRIW DVRTGMCVKT LPAHSDPVSA VSFNRDGSLI TSGSYDGLVR IWDTANGQCV
     KTLVDDENPP VAFVKFSPNG KYILSSNLDN TLKLWDFGKG KTLKQYQGHE NNKYCIFANF
     SVTGGKWIIS GSEDCKIYVW NLQTKEVVQS LEGHTQAVIA SDCHPMQNMI ASGALEPDNT
     IRIWRSDS