ID   TG250_CAEEL             Reviewed;         610 AA.
AC   P34344; C8JQN7; Q4TTD4;
DT   01-FEB-1994, integrated into UniProtKB/Swiss-Prot.
DT   06-JUN-2002, sequence version 2.
DT   03-AUG-2022, entry version 129.
DE   RecName: Full=Putative protein tag-250;
GN   Name=tag-250; ORFNames=C29E4.5;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=7906398; DOI=10.1038/368032a0;
RA   Wilson R., Ainscough R., Anderson K., Baynes C., Berks M., Bonfield J.,
RA   Burton J., Connell M., Copsey T., Cooper J., Coulson A., Craxton M.,
RA   Dear S., Du Z., Durbin R., Favello A., Fraser A., Fulton L., Gardner A.,
RA   Green P., Hawkins T., Hillier L., Jier M., Johnston L., Jones M.,
RA   Kershaw J., Kirsten J., Laisster N., Latreille P., Lightning J., Lloyd C.,
RA   Mortimore B., O'Callaghan M., Parsons J., Percy C., Rifken L., Roopra A.,
RA   Saunders D., Shownkeen R., Sims M., Smaldon N., Smith A., Smith M.,
RA   Sonnhammer E., Staden R., Sulston J., Thierry-Mieg J., Thomas K.,
RA   Vaudin M., Vaughan K., Waterston R., Watson A., Weinstock L.,
RA   Wilkinson-Sproat J., Wohldman P.;
RT   "2.2 Mb of contiguous nucleotide sequence from chromosome III of C.
RT   elegans.";
RL   Nature 368:32-38(1994).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND ALTERNATIVE SPLICING.
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
CC   -!- INTERACTION:
CC       P34344; Q9XUJ2: CELE_W09D6.5; NbExp=4; IntAct=EBI-2414102, EBI-2414107;
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing; Named isoforms=2;
CC       Name=a;
CC         IsoId=P34344-1; Sequence=Displayed;
CC       Name=b;
CC         IsoId=P34344-2; Sequence=VSP_015953, VSP_015954;
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CCD66014.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC       Sequence=CCD66015.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; FO080706; CCD66014.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; FO080706; CCD66015.1; ALT_SEQ; Genomic_DNA.
DR   PIR; S44773; S44773.
DR   RefSeq; NP_001021188.2; NM_001026017.3.
DR   RefSeq; NP_001021189.2; NM_001026018.2.
DR   AlphaFoldDB; P34344; -.
DR   BioGRID; 41320; 1.
DR   IntAct; P34344; 2.
DR   STRING; 6239.C29E4.5a; -.
DR   EPD; P34344; -.
DR   PaxDb; P34344; -.
DR   PeptideAtlas; P34344; -.
DR   EnsemblMetazoa; C29E4.5a.1; C29E4.5a.1; WBGene00016203.
DR   EnsemblMetazoa; C29E4.5b.1; C29E4.5b.1; WBGene00016203.
DR   EnsemblMetazoa; C29E4.5b.2; C29E4.5b.2; WBGene00016203.
DR   GeneID; 176113; -.
DR   KEGG; cel:CELE_C29E4.5; -.
DR   UCSC; C29E4.5a; c. elegans. [P34344-1]
DR   CTD; 176113; -.
DR   WormBase; C29E4.5a; CE43801; WBGene00016203; tag-250.
DR   WormBase; C29E4.5b; CE43781; WBGene00016203; tag-250.
DR   eggNOG; ENOG502S9EE; Eukaryota.
DR   HOGENOM; CLU_478355_0_0_1; -.
DR   InParanoid; P34344; -.
DR   OrthoDB; 367599at2759; -.
DR   PRO; PR:P34344; -.
DR   Proteomes; UP000001940; Chromosome III.
DR   Bgee; WBGene00016203; Expressed in pharyngeal muscle cell (C elegans) and 4 other tissues.
DR   GO; GO:0043186; C:P granule; IBA:GO_Central.
DR   GO; GO:0030719; P:P granule organization; IBA:GO_Central.
DR   GO; GO:0034587; P:piRNA metabolic process; IBA:GO_Central.
DR   Gene3D; 2.40.50.90; -; 1.
DR   InterPro; IPR035437; SNase_OB-fold_sf.
DR   InterPro; IPR002999; Tudor.
DR   Pfam; PF00567; TUDOR; 2.
DR   SMART; SM00333; TUDOR; 2.
PE   1: Evidence at protein level;
KW   Alternative splicing; Reference proteome; Repeat.
FT   CHAIN           1..610
FT                   /note="Putative protein tag-250"
FT                   /id="PRO_0000183184"
FT   DOMAIN          149..260
FT                   /note="Tudor 1"
FT   DOMAIN          386..506
FT                   /note="Tudor 2"
FT   VAR_SEQ         114..136
FT                   /note="VISTDREPTADELKKIKQRKENE -> ACPIRINTTPPLSSLTLIRIWRN
FT                   (in isoform b)"
FT                   /evidence="ECO:0000305"
FT                   /id="VSP_015953"
FT   VAR_SEQ         137..610
FT                   /note="Missing (in isoform b)"
FT                   /evidence="ECO:0000305"
FT                   /id="VSP_015954"
SQ   SEQUENCE   610 AA;  67333 MW;  2E5F0412B52BC544 CRC64;
     MSAVNGLVPS TIFDRINSDM DVSEEMEEIR EVLYEMIKTN FPMGVAATHL SEKYHEEFVS
     KGLGRELPED WIQQVTAAEE FEAQTRGPIT ILFVRLSNTS SFKRPPINSV NVRVISTDRE
     PTADELKKIK QRKENEPTEH AKTLSQQSVA LKEGSTVSIV YADSPKRFFI RALADDDQYE
     KIGTTLAEIY AQETPPSALD SRVAIYEIVA GGAYALQDSN GTWFRVIAKQ PPQSGQVMCH
     FVDVGVCEKF PVAAIRLLPP AVHPVMSIGS MAREVRMDVS EEESLRLNNK FVDLTFETKD
     DGIQVPINLT LSKFDSSDSE SLPVVDLQSS DGLSITEFLK KPSGVVRLST PTKTTSPITP
     ASASTSSLTC LFDKPATIQP MTVAQMPMSA FPANAIFAAG PTDISLRQLS LDPMPDYMYA
     KLKDECALPD SQLESSPDFG GFYAAFIDDR WERVQCIRAS KIDKQAYCVY LLDVGAFQYV
     RKEAMRRLNS TSPFKKMLMF KCKIGGIKPV AGGEVWSRES HEAVREFFEA ACGEPVVVEP
     TQPGWSQWKQ LNAPAVPTCE ARLSCCGRDI GDWLIACGLA LPINAPIPSP NSQSLLTFVP
     TPINIVGRNI