TGA7_ARATH
ID TGA7_ARATH Reviewed; 368 AA.
AC Q93ZE2; Q9SH09;
DT 01-MAR-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-DEC-2001, sequence version 1.
DT 03-AUG-2022, entry version 145.
DE RecName: Full=Transcription factor TGA7;
DE AltName: Full=bZIP transcription factor 50;
DE Short=AtbZIP50;
GN Name=TGA7; Synonyms=BZIP50; OrderedLocusNames=At1g77920;
GN ORFNames=F28K19.13;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], GENE FAMILY, AND NOMENCLATURE.
RC STRAIN=cv. Columbia;
RX PubMed=11906833; DOI=10.1016/s1360-1385(01)02223-3;
RA Jakoby M., Weisshaar B., Droege-Laser W., Vicente-Carbajosa J.,
RA Tiedemann J., Kroj T., Parcy F.;
RT "bZIP transcription factors in Arabidopsis.";
RL Trends Plant Sci. 7:106-111(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP FUNCTION, AND INTERACTION WITH NPR1.
RX PubMed=12953119; DOI=10.1105/tpc.012849;
RA Despres C., Chubak C., Rochon A., Clark R., Bethune T., Desveaux D.,
RA Fobert P.R.;
RT "The Arabidopsis NPR1 disease resistance protein is a novel cofactor that
RT confers redox regulation of DNA binding activity to the basic
RT domain/leucine zipper transcription factor TGA1.";
RL Plant Cell 15:2181-2191(2003).
RN [6]
RP INTERACTION WITH NPR1 AND NPR4.
RX PubMed=15634206; DOI=10.1111/j.1365-313x.2004.02296.x;
RA Liu G., Holub E.B., Alonso J.M., Ecker J.R., Fobert P.R.;
RT "An Arabidopsis NPR1-like gene, NPR4, is required for disease resistance.";
RL Plant J. 41:304-318(2005).
RN [7]
RP INTERACTION WITH GRXC7/ROXY1.
RX PubMed=19218396; DOI=10.1105/tpc.108.064477;
RA Li S., Lauri A., Ziemann M., Busch A., Bhave M., Zachgo S.;
RT "Nuclear activity of ROXY1, a glutaredoxin interacting with TGA factors, is
RT required for petal development in Arabidopsis thaliana.";
RL Plant Cell 21:429-441(2009).
CC -!- FUNCTION: Transcriptional activator that binds specifically to the DNA
CC sequence 5'-TGACG-3'. Recognizes ocs elements like the as-1 motif of
CC the cauliflower mosaic virus 35S promoter. Binding to the as-1-like cis
CC elements mediate auxin- and salicylic acid-inducible transcription. May
CC be involved in the induction of the systemic acquired resistance (SAR)
CC via its interaction with NPR1 (By similarity). {ECO:0000250,
CC ECO:0000269|PubMed:12953119}.
CC -!- SUBUNIT: Binds DNA as a dimer. Interacts with NPR1 and NPR4. Interacts
CC with GRXC7/ROXY1. {ECO:0000269|PubMed:12953119,
CC ECO:0000269|PubMed:15634206, ECO:0000269|PubMed:19218396}.
CC -!- INTERACTION:
CC Q93ZE2; C0SUZ3: At1g35490; NbExp=3; IntAct=EBI-541400, EBI-15192249;
CC Q93ZE2; F4JI72: At4g03250; NbExp=4; IntAct=EBI-541400, EBI-15192535;
CC Q93ZE2; Q0V7X4: FIT; NbExp=3; IntAct=EBI-541400, EBI-1640543;
CC Q93ZE2; Q96305: GRXC7; NbExp=3; IntAct=EBI-541400, EBI-2257898;
CC Q93ZE2; Q84XV2: GTE1; NbExp=3; IntAct=EBI-541400, EBI-25515825;
CC Q93ZE2; O82277: TCP10; NbExp=4; IntAct=EBI-541400, EBI-3133327;
CC Q93ZE2; Q8LPR5: TCP4; NbExp=3; IntAct=EBI-541400, EBI-15192325;
CC Q93ZE2; P43273: TGA2; NbExp=3; IntAct=EBI-541400, EBI-541307;
CC Q93ZE2; Q39163: TGA5; NbExp=7; IntAct=EBI-541400, EBI-541381;
CC -!- SUBCELLULAR LOCATION: Nucleus.
CC -!- SIMILARITY: Belongs to the bZIP family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAF17682.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC Sequence=CAC42910.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; AJ315736; CAC42910.1; ALT_INIT; mRNA.
DR EMBL; AC009243; AAF17682.1; ALT_INIT; Genomic_DNA.
DR EMBL; CP002684; AEE36045.1; -; Genomic_DNA.
DR EMBL; AY057596; AAL14391.1; -; mRNA.
DR EMBL; BT010164; AAQ22633.1; -; mRNA.
DR RefSeq; NP_565162.1; NM_106441.4.
DR AlphaFoldDB; Q93ZE2; -.
DR SMR; Q93ZE2; -.
DR BioGRID; 29346; 26.
DR IntAct; Q93ZE2; 26.
DR STRING; 3702.AT1G77920.1; -.
DR PaxDb; Q93ZE2; -.
DR PRIDE; Q93ZE2; -.
DR ProteomicsDB; 246402; -.
DR EnsemblPlants; AT1G77920.1; AT1G77920.1; AT1G77920.
DR GeneID; 844127; -.
DR Gramene; AT1G77920.1; AT1G77920.1; AT1G77920.
DR KEGG; ath:AT1G77920; -.
DR Araport; AT1G77920; -.
DR TAIR; locus:2029366; AT1G77920.
DR eggNOG; ENOG502QS1H; Eukaryota.
DR HOGENOM; CLU_024782_1_0_1; -.
DR InParanoid; Q93ZE2; -.
DR OMA; AYANGNM; -.
DR OrthoDB; 752703at2759; -.
DR PhylomeDB; Q93ZE2; -.
DR PRO; PR:Q93ZE2; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q93ZE2; baseline and differential.
DR Genevisible; Q93ZE2; AT.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IPI:TAIR.
DR GO; GO:0042742; P:defense response to bacterium; IMP:TAIR.
DR GO; GO:0006351; P:transcription, DNA-templated; IEA:InterPro.
DR InterPro; IPR004827; bZIP.
DR InterPro; IPR046347; bZIP_sf.
DR InterPro; IPR025422; TGA_domain.
DR Pfam; PF00170; bZIP_1; 1.
DR Pfam; PF14144; DOG1; 1.
DR SMART; SM00338; BRLZ; 1.
DR SUPFAM; SSF57959; SSF57959; 1.
DR PROSITE; PS50217; BZIP; 1.
DR PROSITE; PS00036; BZIP_BASIC; 1.
DR PROSITE; PS51806; DOG1; 1.
PE 1: Evidence at protein level;
KW Activator; Coiled coil; DNA-binding; Nucleus; Reference proteome;
KW Transcription; Transcription regulation.
FT CHAIN 1..368
FT /note="Transcription factor TGA7"
FT /id="PRO_0000076559"
FT DOMAIN 91..151
FT /note="bZIP"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00978"
FT DOMAIN 152..363
FT /note="DOG1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01147"
FT REGION 70..89
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 93..113
FT /note="Basic motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00978"
FT REGION 119..133
FT /note="Leucine-zipper"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00978"
FT COILED 92..142
FT /evidence="ECO:0000255"
FT COILED 252..285
FT /evidence="ECO:0000255"
SQ SEQUENCE 368 AA; 41913 MW; 3C6CBF4D070C2D0A CRC64;
MMSSSSPTQL ASLRDMGIYE PFQQIVGWGN VFKSDINDHS PNTATSSIIQ VDPRIDDHNN
NIKINYDSSH NQIEAEQPSS NDNQDDDGRI HDKMKRRLAQ NREAARKSRL RKKAYVQQLE
ESRLKLSQLE QELEKVKQQG HLGPSGSINT GIASFEMEYS HWLQEQSRRV SELRTALQSH
ISDIELKMLV ESCLNHYANL FQMKSDAAKA DVFYLISGMW RTSTERFFQW IGGFRPSELL
NVVMPYLQPL TDQQILEVRN LQQSSQQAED ALSQGIDKLQ QSLAESIVID AVIESTHYPT
HMAAAIENLQ ALEGFVNQAD HLRQQTLQQM AKILTTRQSA RGLLALGEYL HRLRALSSLW
AARPQEPT
