ID   TGB2_FXMV               Reviewed;         127 AA.
AC   P22170; B1NLP6;
DT   01-AUG-1991, integrated into UniProtKB/Swiss-Prot.
DT   28-JUN-2011, sequence version 2.
DT   07-OCT-2020, entry version 70.
DE   RecName: Full=Movement protein TGB2;
DE   AltName: Full=12 kDa protein;
DE   AltName: Full=Triple gene block 2 protein;
DE            Short=TGBp2;
GN   ORFNames=ORF3;
OS   Foxtail mosaic virus.
OC   Viruses; Riboviria; Orthornavirae; Kitrinoviricota; Alsuviricetes;
OC   Tymovirales; Alphaflexiviridae; Potexvirus.
OX   NCBI_TaxID=12179;
OH   NCBI_TaxID=4555; Setaria italica (Foxtail millet) (Panicum italicum).
OH   NCBI_TaxID=4556; Setaria viridis (Green bristlegrass) (Setaria italica subsp. viridis).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=1840610; DOI=10.1099/0022-1317-72-9-2173;
RA   Bancroft J.B., Rouleau M., Johnston R., Prins L., Mackie G.A.;
RT   "The entire nucleotide sequence of foxtail mosaic virus RNA.";
RL   J. Gen. Virol. 72:2173-2181(1991).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=17955161; DOI=10.1007/s00705-007-1057-3;
RA   Bruun-Rasmussen M., Madsen C.T., Johansen E., Albrechtsen M.;
RT   "Revised sequence of foxtail mosaic virus reveals a triple gene block
RT   structure similar to potato virus X.";
RL   Arch. Virol. 153:223-226(2008).
RN   [3]
RP   REVIEW.
RX   PubMed=15828680; DOI=10.1094/mpmi-18-0283;
RA   Verchot-Lubicz J.;
RT   "A new cell-to-cell transport model for Potexviruses.";
RL   Mol. Plant Microbe Interact. 18:283-290(2005).
CC   -!- FUNCTION: Plays a role in viral cell-to-cell propagation, by
CC       facilitating genome transport to neighboring plant cells through
CC       plasmosdesmata,. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Host endoplasmic reticulum membrane
CC       {ECO:0000250}.
CC   -!- MISCELLANEOUS: TGBp1, TGBp2 and TGBp3 seem to act together for cell-to-
CC       cell propagation. TGBp1 is the main movement protein that physically
CC       cross the plasmodesma with the viral genome. TGBp2 and TGBp3 would
CC       facilitate TGBp1 function.
CC   -!- SIMILARITY: Belongs to the Tymovirales TGBp2 protein family.
CC       {ECO:0000305}.
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DR   EMBL; M62730; AAA43828.1; -; Genomic_RNA.
DR   EMBL; EF630359; ABW25050.1; -; Genomic_RNA.
DR   EMBL; EF630360; ABW25056.1; -; Genomic_RNA.
DR   PIR; JQ1260; JQ1260.
DR   RefSeq; NP_040990.1; NC_001483.1.
DR   GeneID; 1494011; -.
DR   KEGG; vg:1494011; -.
DR   Proteomes; UP000008623; Genome.
DR   GO; GO:0044167; C:host cell endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0046740; P:transport of virus in host, cell to cell; IEA:UniProtKB-KW.
DR   InterPro; IPR001896; Plant_vir_prot.
DR   Pfam; PF01307; Plant_vir_prot; 1.
PE   3: Inferred from homology;
KW   Host endoplasmic reticulum; Host membrane; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix; Transport; Viral movement protein.
FT   CHAIN           1..127
FT                   /note="Movement protein TGB2"
FT                   /id="PRO_0000222583"
FT   TOPO_DOM        1..24
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000250"
FT   TRANSMEM        25..45
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        46..85
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000250"
FT   TRANSMEM        86..106
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        107..127
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000250"
FT   CONFLICT        5
FT                   /note="H -> Q (in Ref. 1; AAA43828)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        31
FT                   /note="I -> V (in Ref. 1; AAA43828)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        88..113
FT                   /note="AFAPPILAAVLFFLTQPYLATRRSRC -> VSLHQYSPQYSFSSHSHI (in
FT                   Ref. 1; AAA43828)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   127 AA;  13637 MW;  CCA7BD0D276C92CB CRC64;
     MSLSHGTGAP AISTPLTLRP PPDNTKAILT IAIGIAASLV FFMLTRNNLP HVGDNIHSLP
     HGGSYIDGTK SINYRPPASR YPSSNLLAFA PPILAAVLFF LTQPYLATRR SRCVRCFVVH
     GACTNHT