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TGB2_NMV
ID   TGB2_NMV                Reviewed;         130 AA.
AC   P15097;
DT   01-APR-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-APR-1990, sequence version 1.
DT   02-JUN-2021, entry version 74.
DE   RecName: Full=Movement protein TGB2;
DE   AltName: Full=14 kDa protein;
DE   AltName: Full=Triple gene block 2 protein;
DE            Short=TGBp2;
GN   ORFNames=ORF3;
OS   Narcissus mosaic virus (NMV).
OC   Viruses; Riboviria; Orthornavirae; Kitrinoviricota; Alsuviricetes;
OC   Tymovirales; Alphaflexiviridae; Potexvirus.
OX   NCBI_TaxID=12180;
OH   NCBI_TaxID=39639; Narcissus pseudonarcissus (Daffodil).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=2732689; DOI=10.1099/0022-1317-70-2-267;
RA   Zuidema D., Linthorst H.J.M., Huisman M.J., Asjes C.J., Bol J.F.;
RT   "Nucleotide sequence of narcissus mosaic virus RNA.";
RL   J. Gen. Virol. 70:267-276(1989).
RN   [2]
RP   REVIEW.
RX   PubMed=15828680; DOI=10.1094/mpmi-18-0283;
RA   Verchot-Lubicz J.;
RT   "A new cell-to-cell transport model for Potexviruses.";
RL   Mol. Plant Microbe Interact. 18:283-290(2005).
CC   -!- FUNCTION: Plays a role in viral cell-to-cell propagation, by
CC       facilitating genome transport to neighboring plant cells through
CC       plasmosdesmata,. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Host endoplasmic reticulum membrane
CC       {ECO:0000250}.
CC   -!- MISCELLANEOUS: TGBp1, TGBp2 and TGBp3 seem to act together for cell-to-
CC       cell propagation. TGBp1 is the main movement protein that physically
CC       cross the plasmodesma with the viral genome. TGBp2 and TGBp3 would
CC       facilitate TGBp1 function.
CC   -!- SIMILARITY: Belongs to the Tymovirales TGBp2 protein family.
CC       {ECO:0000305}.
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DR   EMBL; D13747; BAA02893.1; -; Genomic_RNA.
DR   PIR; JT0472; WMWGN2.
DR   RefSeq; NP_040780.1; NC_001441.1.
DR   GeneID; 1494018; -.
DR   KEGG; vg:1494018; -.
DR   Proteomes; UP000008865; Genome.
DR   GO; GO:0044167; C:host cell endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0046740; P:transport of virus in host, cell to cell; IEA:UniProtKB-KW.
DR   InterPro; IPR001896; Plant_vir_prot.
DR   Pfam; PF01307; Plant_vir_prot; 1.
PE   3: Inferred from homology;
KW   Host endoplasmic reticulum; Host membrane; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix; Transport; Viral movement protein.
FT   CHAIN           1..130
FT                   /note="Movement protein TGB2"
FT                   /id="PRO_0000222585"
FT   TOPO_DOM        1..12
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000250"
FT   TRANSMEM        13..30
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        31..72
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000250"
FT   TRANSMEM        73..90
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        91..130
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000250"
FT   REGION          110..130
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   130 AA;  13998 MW;  6BB740A54AEB1DDA CRC64;
     MPGLTPPVNY EQVYKVLAIG FLLCASIYCL RSNHLPHVGD NIHSLPHGGN YADGTKRVQY
     FRPHSSTSTN HKYTALCAVL TLSLLIFAQT RLAAGNRITS VSICHHCSSQ GSLSGGNHGR
     VSGHSELPTT
 
 
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