TGB2_NMV
ID TGB2_NMV Reviewed; 130 AA.
AC P15097;
DT 01-APR-1990, integrated into UniProtKB/Swiss-Prot.
DT 01-APR-1990, sequence version 1.
DT 02-JUN-2021, entry version 74.
DE RecName: Full=Movement protein TGB2;
DE AltName: Full=14 kDa protein;
DE AltName: Full=Triple gene block 2 protein;
DE Short=TGBp2;
GN ORFNames=ORF3;
OS Narcissus mosaic virus (NMV).
OC Viruses; Riboviria; Orthornavirae; Kitrinoviricota; Alsuviricetes;
OC Tymovirales; Alphaflexiviridae; Potexvirus.
OX NCBI_TaxID=12180;
OH NCBI_TaxID=39639; Narcissus pseudonarcissus (Daffodil).
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX PubMed=2732689; DOI=10.1099/0022-1317-70-2-267;
RA Zuidema D., Linthorst H.J.M., Huisman M.J., Asjes C.J., Bol J.F.;
RT "Nucleotide sequence of narcissus mosaic virus RNA.";
RL J. Gen. Virol. 70:267-276(1989).
RN [2]
RP REVIEW.
RX PubMed=15828680; DOI=10.1094/mpmi-18-0283;
RA Verchot-Lubicz J.;
RT "A new cell-to-cell transport model for Potexviruses.";
RL Mol. Plant Microbe Interact. 18:283-290(2005).
CC -!- FUNCTION: Plays a role in viral cell-to-cell propagation, by
CC facilitating genome transport to neighboring plant cells through
CC plasmosdesmata,. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Host endoplasmic reticulum membrane
CC {ECO:0000250}.
CC -!- MISCELLANEOUS: TGBp1, TGBp2 and TGBp3 seem to act together for cell-to-
CC cell propagation. TGBp1 is the main movement protein that physically
CC cross the plasmodesma with the viral genome. TGBp2 and TGBp3 would
CC facilitate TGBp1 function.
CC -!- SIMILARITY: Belongs to the Tymovirales TGBp2 protein family.
CC {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; D13747; BAA02893.1; -; Genomic_RNA.
DR PIR; JT0472; WMWGN2.
DR RefSeq; NP_040780.1; NC_001441.1.
DR GeneID; 1494018; -.
DR KEGG; vg:1494018; -.
DR Proteomes; UP000008865; Genome.
DR GO; GO:0044167; C:host cell endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0046740; P:transport of virus in host, cell to cell; IEA:UniProtKB-KW.
DR InterPro; IPR001896; Plant_vir_prot.
DR Pfam; PF01307; Plant_vir_prot; 1.
PE 3: Inferred from homology;
KW Host endoplasmic reticulum; Host membrane; Membrane; Reference proteome;
KW Transmembrane; Transmembrane helix; Transport; Viral movement protein.
FT CHAIN 1..130
FT /note="Movement protein TGB2"
FT /id="PRO_0000222585"
FT TOPO_DOM 1..12
FT /note="Cytoplasmic"
FT /evidence="ECO:0000250"
FT TRANSMEM 13..30
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 31..72
FT /note="Lumenal"
FT /evidence="ECO:0000250"
FT TRANSMEM 73..90
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 91..130
FT /note="Cytoplasmic"
FT /evidence="ECO:0000250"
FT REGION 110..130
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 130 AA; 13998 MW; 6BB740A54AEB1DDA CRC64;
MPGLTPPVNY EQVYKVLAIG FLLCASIYCL RSNHLPHVGD NIHSLPHGGN YADGTKRVQY
FRPHSSTSTN HKYTALCAVL TLSLLIFAQT RLAAGNRITS VSICHHCSSQ GSLSGGNHGR
VSGHSELPTT