ID   TGB2_PCV87              Reviewed;         122 AA.
AC   Q08315;
DT   31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   23-FEB-2022, entry version 52.
DE   RecName: Full=Movement protein TGB2;
DE   AltName: Full=P14;
DE   AltName: Full=Triple gene block 2 protein;
DE            Short=TGBp2;
OS   Peanut clump virus (isolate 87/TGTA2) (PCV).
OC   Viruses; Riboviria; Orthornavirae; Kitrinoviricota; Alsuviricetes;
OC   Martellivirales; Virgaviridae; Pecluvirus.
OX   NCBI_TaxID=652837;
OH   NCBI_TaxID=3818; Arachis hypogaea (Peanut).
OH   NCBI_TaxID=4555; Setaria italica (Foxtail millet) (Panicum italicum).
OH   NCBI_TaxID=91525; Sorghum arundinaceum.
OH   NCBI_TaxID=4558; Sorghum bicolor (Sorghum) (Sorghum vulgare).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=8317107; DOI=10.1006/viro.1993.1343;
RA   Manohar S.K., Guilley H., Dollet M., Richards K., Jonard G.;
RT   "Nucleotide sequence and genetic organization of peanut clump virus RNA 2
RT   and partial characterization of deleted forms.";
RL   Virology 195:33-41(1993).
RN   [2]
RP   FUNCTION.
RX   PubMed=9721240; DOI=10.1006/viro.1998.9287;
RA   Herzog E., Hemmer O., Hauser S., Meyer G., Bouzoubaa S., Fritsch C.;
RT   "Identification of genes involved in replication and movement of peanut
RT   clump virus.";
RL   Virology 248:312-322(1998).
CC   -!- FUNCTION: Participates in the transport of viral genome to neighboring
CC       plant cells directly through plasmodesmata, without any budding
CC       (PubMed:9721240). TGBp2 and TGBp3 are necessary for intracellular
CC       delivery of TGBp1-containing vRNPs to plasmodesmata (By similarity).
CC       Can gate plasmodesmata and increase their size exclusion limit (By
CC       similarity). To a lesser extent than TGB3, induces host actin
CC       cytoskeleton network thickening, which probably plays a major role in
CC       virus cell-to-cell movement (By similarity).
CC       {ECO:0000250|UniProtKB:P04869, ECO:0000269|PubMed:9721240}.
CC   -!- SUBUNIT: Interacts with movement protein TGB3. TGB1-TGB3-TGB2 complex
CC       formation is enhanced by ATP hydrolysis.
CC       {ECO:0000250|UniProtKB:P04869}.
CC   -!- SUBCELLULAR LOCATION: Host cell junction, host plasmodesma
CC       {ECO:0000250|UniProtKB:P04869}. Host endoplasmic reticulum membrane
CC       {ECO:0000250|UniProtKB:P04869}; Multi-pass membrane protein
CC       {ECO:0000250|UniProtKB:Q9IV53}. Host cytoplasm, host cytoskeleton
CC       {ECO:0000250|UniProtKB:P04869}. Note=Probably localizes to
CC       plasmodesmata-associated membrane compartments called peripheral
CC       membrane bodies (PMBs). Associates with host actin filaments, possibly
CC       for the intracellular transport to the plasmodesmata (By similarity).
CC       The viral replication sites are located at the host chloroplast
CC       membrane (By similarity). {ECO:0000250|UniProtKB:P04869,
CC       ECO:0000250|UniProtKB:Q9IV52}.
CC   -!- SIMILARITY: Belongs to the virgaviridae/benyvirus TGB2 movement protein
CC       family. {ECO:0000305}.
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DR   EMBL; L07269; AAA17439.1; -; Unassigned_DNA.
DR   RefSeq; NP_620031.1; NC_003668.1.
DR   GeneID; 991041; -.
DR   KEGG; vg:991041; -.
DR   Proteomes; UP000001668; Genome.
DR   GO; GO:0044167; C:host cell endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0044219; C:host cell plasmodesma; IEA:UniProtKB-SubCell.
DR   GO; GO:0044163; C:host cytoskeleton; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0046740; P:transport of virus in host, cell to cell; IEA:UniProtKB-KW.
DR   InterPro; IPR001896; Plant_vir_prot.
DR   Pfam; PF01307; Plant_vir_prot; 1.
PE   3: Inferred from homology;
KW   Host cell junction; Host cytoplasm; Host cytoskeleton;
KW   Host endoplasmic reticulum; Host membrane; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix; Transport; Viral movement protein.
FT   CHAIN           1..122
FT                   /note="Movement protein TGB2"
FT                   /id="PRO_0000409150"
FT   TOPO_DOM        1..12
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000250|UniProtKB:Q9IV53"
FT   TRANSMEM        13..33
FT                   /note="Helical"
FT                   /evidence="ECO:0000250|UniProtKB:Q9IV53"
FT   TOPO_DOM        34..76
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000250|UniProtKB:Q9IV53"
FT   TRANSMEM        77..97
FT                   /note="Helical"
FT                   /evidence="ECO:0000250|UniProtKB:Q9IV53"
FT   TOPO_DOM        98..122
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000250|UniProtKB:Q9IV53"
SQ   SEQUENCE   122 AA;  13771 MW;  72D9E82718CF2AAD CRC64;
     MVKSTVPTRP NKYWPGVVAI GLVSLFIFLS VSNQKHSTTS GDNIHKFSNG GTYRDGSKCI
     TYNRNSPLAY NGSSSNNTLF WLCLLGLSMV WIAYCGYKSL SGQWHSCQHD KNERNFLFEC
     FE