TGB2_PMV
ID TGB2_PMV Reviewed; 111 AA.
AC P20953;
DT 01-FEB-1991, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1991, sequence version 1.
DT 02-DEC-2020, entry version 73.
DE RecName: Full=Movement protein TGB2;
DE AltName: Full=12 kDa protein;
DE AltName: Full=Triple gene block 2 protein;
DE Short=TGBp2;
GN ORFNames=ORF3;
OS Papaya mosaic potexvirus (PMV).
OC Viruses; Riboviria; Orthornavirae; Kitrinoviricota; Alsuviricetes;
OC Tymovirales; Alphaflexiviridae; Potexvirus.
OX NCBI_TaxID=12181;
OH NCBI_TaxID=3649; Carica papaya (Papaya).
OH NCBI_TaxID=108055; Ullucus tuberosus (Olluco).
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX PubMed=2778435; DOI=10.1099/0022-1317-70-9-2325;
RA Sit T.L., Abouhaidar M.G., Holy S.;
RT "Nucleotide sequence of papaya mosaic virus RNA.";
RL J. Gen. Virol. 70:2325-2331(1989).
RN [2]
RP REVIEW.
RX PubMed=15828680; DOI=10.1094/mpmi-18-0283;
RA Verchot-Lubicz J.;
RT "A new cell-to-cell transport model for Potexviruses.";
RL Mol. Plant Microbe Interact. 18:283-290(2005).
CC -!- FUNCTION: Plays a role in viral cell-to-cell propagation, by
CC facilitating genome transport to neighboring plant cells through
CC plasmosdesmata,. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Host endoplasmic reticulum membrane
CC {ECO:0000250}.
CC -!- MISCELLANEOUS: TGBp1, TGBp2 and TGBp3 seem to act together for cell-to-
CC cell propagation. TGBp1 is the main movement protein that physically
CC cross the plasmodesma with the viral genome. TGBp2 and TGBp3 would
CC facilitate TGBp1 function.
CC -!- SIMILARITY: Belongs to the Tymovirales TGBp2 protein family.
CC {ECO:0000305}.
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DR EMBL; D13957; BAA03052.1; -; Genomic_RNA.
DR PIR; JQ0098; JQ0098.
DR RefSeq; NP_044332.1; NC_001748.1.
DR GeneID; 1494023; -.
DR KEGG; vg:1494023; -.
DR Proteomes; UP000000477; Genome.
DR GO; GO:0044167; C:host cell endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0046740; P:transport of virus in host, cell to cell; IEA:UniProtKB-KW.
DR InterPro; IPR001896; Plant_vir_prot.
DR Pfam; PF01307; Plant_vir_prot; 1.
PE 3: Inferred from homology;
KW Host endoplasmic reticulum; Host membrane; Membrane; Reference proteome;
KW Transmembrane; Transmembrane helix; Transport; Viral movement protein.
FT CHAIN 1..111
FT /note="Movement protein TGB2"
FT /id="PRO_0000222587"
FT TOPO_DOM 1..16
FT /note="Cytoplasmic"
FT /evidence="ECO:0000250"
FT TRANSMEM 17..37
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 38..72
FT /note="Lumenal"
FT /evidence="ECO:0000250"
FT TRANSMEM 73..93
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 94..111
FT /note="Cytoplasmic"
FT /evidence="ECO:0000250"
SQ SEQUENCE 111 AA; 11950 MW; 60CBBE9CB0F585B0 CRC64;
MSSHQNFLTP PPDHSKAILA VAVGVGLAIV LHFSLSYKLP SPGDNIHSLP FGGTYRDGTK
SIIYNSPHRG PGQSGALPII TVFAIIECTL HVLRKRDNPV RPQHSDCPNC S