ID   TGB2_PVSP               Reviewed;         108 AA.
AC   P16651;
DT   01-AUG-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1990, sequence version 1.
DT   07-OCT-2020, entry version 61.
DE   RecName: Full=Movement protein TGB2;
DE   AltName: Full=12 kDa protein;
DE   AltName: Full=Triple gene block 2 protein;
DE            Short=TGBp2;
GN   ORFNames=ORF3;
OS   Potato virus S (strain Peruvian).
OC   Viruses; Riboviria; Orthornavirae; Kitrinoviricota; Alsuviricetes;
OC   Tymovirales; Betaflexiviridae; Quinvirinae; Carlavirus.
OX   NCBI_TaxID=12170;
OH   NCBI_TaxID=4113; Solanum tuberosum (Potato).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=2732711; DOI=10.1099/0022-1317-70-5-1053;
RA   Mackenzie D.J., Tremaine J.H., Stace-Smith R.;
RT   "Organization and interviral homologies of the 3'-terminal portion of
RT   potato virus S RNA.";
RL   J. Gen. Virol. 70:1053-1063(1989).
CC   -!- FUNCTION: Plays a role in viral cell-to-cell propagation, by
CC       facilitating genome transport to neighboring plant cells through
CC       plasmosdesmata,. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Host endoplasmic reticulum membrane
CC       {ECO:0000250}.
CC   -!- MISCELLANEOUS: TGBp1, TGBp2 and TGBp3 seem to act together for cell-to-
CC       cell propagation. TGBp1 is the main movement protein that physically
CC       cross the plasmodesma with the viral genome. TGBp2 and TGBp3 would
CC       facilitate TGBp1 function.
CC   -!- SIMILARITY: Belongs to the Tymovirales TGBp2 protein family.
CC       {ECO:0000305}.
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DR   EMBL; D00461; BAA00352.1; -; Genomic_RNA.
DR   PIR; JA0125; JA0125.
DR   GO; GO:0044167; C:host cell endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0046740; P:transport of virus in host, cell to cell; IEA:UniProtKB-KW.
DR   InterPro; IPR001896; Plant_vir_prot.
DR   Pfam; PF01307; Plant_vir_prot; 1.
PE   3: Inferred from homology;
KW   Host endoplasmic reticulum; Host membrane; Membrane; Transmembrane;
KW   Transmembrane helix; Transport; Viral movement protein.
FT   CHAIN           1..108
FT                   /note="Movement protein TGB2"
FT                   /id="PRO_0000222598"
FT   TOPO_DOM        1..8
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000250"
FT   TRANSMEM        9..29
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        30..72
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000250"
FT   TRANSMEM        73..93
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        94..108
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   108 AA;  11819 MW;  DCD9AA9B07906A66 CRC64;
     MPLTPPPNYT GLYIAAALGV SLAAVVALFT RSTLPIVGDS QHNLPHGGRY RDGTKAIDYF
     KPTKLNSVEP GNYWYTQPWL LVILLVALIC LSGRHAQCCP RCNRVHSA