ID   TGB2_PVX                Reviewed;         115 AA.
AC   P0C787; P07697;
DT   02-NOV-2010, integrated into UniProtKB/Swiss-Prot.
DT   02-NOV-2010, sequence version 1.
DT   03-AUG-2022, entry version 29.
DE   RecName: Full=Movement protein TGB2;
DE   AltName: Full=12 kDa protein;
DE   AltName: Full=Triple gene block 2 protein;
DE            Short=TGBp2;
GN   ORFNames=ORF3;
OS   Potato virus X (PVX).
OC   Viruses; Riboviria; Orthornavirae; Kitrinoviricota; Alsuviricetes;
OC   Tymovirales; Alphaflexiviridae; Potexvirus.
OX   NCBI_TaxID=12183;
OH   NCBI_TaxID=3711; Brassica campestris (Field mustard).
OH   NCBI_TaxID=4113; Solanum tuberosum (Potato).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=3205733; DOI=10.1093/nar/16.22.10929;
RA   Skryabin K.G., Kraev A.S., Morozov S.Y., Rozanov M.N., Chernov B.K.,
RA   Lukasheva L.I., Atabekov J.G.;
RT   "The nucleotide sequence of potato virus X RNA.";
RL   Nucleic Acids Res. 16:10929-10930(1988).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RA   Morozov S.Y., Lukasheva L.I., Chernov B.K., Skryabin K.G., Atabekov J.G.;
RT   "Nucleotide sequence of the open reading frames adjacent to the coat
RT   protein cistron in potato virus X genome.";
RL   FEBS Lett. 213:438-442(1987).
RN   [3]
RP   REVIEW.
RX   PubMed=15828680; DOI=10.1094/mpmi-18-0283;
RA   Verchot-Lubicz J.;
RT   "A new cell-to-cell transport model for Potexviruses.";
RL   Mol. Plant Microbe Interact. 18:283-290(2005).
CC   -!- FUNCTION: Plays a role in viral cell-to-cell propagation, by
CC       facilitating genome transport to neighboring plant cells through
CC       plasmosdesmata,. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Host endoplasmic reticulum membrane
CC       {ECO:0000250}.
CC   -!- MISCELLANEOUS: TGBp1, TGBp2 and TGBp3 seem to act together for cell-to-
CC       cell propagation. TGBp1 is the main movement protein that physically
CC       cross the plasmodesma with the viral genome. TGBp2 and TGBp3 would
CC       facilitate TGBp1 function.
CC   -!- SIMILARITY: Belongs to the Tymovirales TGBp2 protein family.
CC       {ECO:0000305}.
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DR   EMBL; M72416; AAA47169.1; -; Genomic_RNA.
DR   RefSeq; YP_002332931.1; NC_011620.1.
DR   GeneID; 7065756; -.
DR   KEGG; vg:7065756; -.
DR   Proteomes; UP000006841; Genome.
DR   GO; GO:0044167; C:host cell endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0046740; P:transport of virus in host, cell to cell; IEA:UniProtKB-KW.
DR   InterPro; IPR001896; Plant_vir_prot.
DR   Pfam; PF01307; Plant_vir_prot; 1.
PE   3: Inferred from homology;
KW   Host endoplasmic reticulum; Host membrane; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix; Transport; Viral movement protein.
FT   CHAIN           1..115
FT                   /note="Movement protein TGB2"
FT                   /id="PRO_0000222588"
FT   TOPO_DOM        1..13
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000250"
FT   TRANSMEM        14..34
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        35..74
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000250"
FT   TRANSMEM        75..95
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        96..115
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   115 AA;  12338 MW;  029983C61B842C0D CRC64;
     MSAQGHRLTA PVNSEKVYIV LGLSFALVSI TFLLSRNSLP HVGDNIHSLP HGGAYRDGTK
     AILYNSPNLG SRVSLHNGKN AAFAAVLLLT LLIYGSKYIS QRNHTCACGN NHSSH