TGB2_PVXCP
ID TGB2_PVXCP Reviewed; 115 AA.
AC P22593;
DT 01-AUG-1991, integrated into UniProtKB/Swiss-Prot.
DT 01-AUG-1991, sequence version 1.
DT 03-AUG-2022, entry version 73.
DE RecName: Full=Movement protein TGB2;
DE AltName: Full=12 kDa protein;
DE AltName: Full=Triple gene block 2 protein;
DE Short=TGBp2;
GN ORFNames=ORF3;
OS Potato virus X (strain CP) (PVX).
OC Viruses; Riboviria; Orthornavirae; Kitrinoviricota; Alsuviricetes;
OC Tymovirales; Alphaflexiviridae; Potexvirus.
OX NCBI_TaxID=12184;
OH NCBI_TaxID=3711; Brassica campestris (Field mustard).
OH NCBI_TaxID=4113; Solanum tuberosum (Potato).
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX PubMed=2392880; DOI=10.1016/0168-1702(90)90054-f;
RA Orman B.E., Celnik R.M., Mandel A.M., Torres H.N., Mentaberry A.N.;
RT "Complete cDNA sequence of a South American isolate of potato virus X.";
RL Virus Res. 16:293-305(1990).
RN [2]
RP REVIEW.
RX PubMed=15828680; DOI=10.1094/mpmi-18-0283;
RA Verchot-Lubicz J.;
RT "A new cell-to-cell transport model for Potexviruses.";
RL Mol. Plant Microbe Interact. 18:283-290(2005).
CC -!- FUNCTION: Plays a role in viral cell-to-cell propagation, by
CC facilitating genome transport to neighboring plant cells through
CC plasmosdesmata,. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Host endoplasmic reticulum membrane
CC {ECO:0000250}.
CC -!- MISCELLANEOUS: TGBp1, TGBp2 and TGBp3 seem to act together for cell-to-
CC cell propagation. TGBp1 is the main movement protein that physically
CC cross the plasmodesma with the viral genome. TGBp2 and TGBp3 would
CC facilitate TGBp1 function.
CC -!- SIMILARITY: Belongs to the Tymovirales TGBp2 protein family.
CC {ECO:0000305}.
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DR EMBL; X55802; CAA39326.1; -; Genomic_RNA.
DR PIR; S14007; S14007.
DR Proteomes; UP000008615; Genome.
DR GO; GO:0044167; C:host cell endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0046740; P:transport of virus in host, cell to cell; IEA:UniProtKB-KW.
DR InterPro; IPR001896; Plant_vir_prot.
DR Pfam; PF01307; Plant_vir_prot; 1.
PE 3: Inferred from homology;
KW Host endoplasmic reticulum; Host membrane; Membrane; Reference proteome;
KW Transmembrane; Transmembrane helix; Transport; Viral movement protein.
FT CHAIN 1..115
FT /note="Movement protein TGB2"
FT /id="PRO_0000222589"
FT TOPO_DOM 1..13
FT /note="Cytoplasmic"
FT /evidence="ECO:0000250"
FT TRANSMEM 14..34
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 35..74
FT /note="Lumenal"
FT /evidence="ECO:0000250"
FT TRANSMEM 75..95
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 96..115
FT /note="Cytoplasmic"
FT /evidence="ECO:0000250"
SQ SEQUENCE 115 AA; 12318 MW; 25CEE4894F4C1020 CRC64;
MSAQGHRLTA PVNSEKVYIV LGLSFALISI TFLLSRSNLP HVGDNIHSLP HGGAYRDGTK
AVLYNSPNFG SRTSLSNGKN AAFAVVLLLS LLIYGSRCLS QRNHLCACGN NHSSH