ID   TGB2_WCMVM              Reviewed;         116 AA.
AC   P09500;
DT   01-JUL-1989, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1989, sequence version 1.
DT   23-FEB-2022, entry version 90.
DE   RecName: Full=Movement protein TGB2;
DE   AltName: Full=13 kDa protein;
DE   AltName: Full=Triple gene block 2 protein;
DE            Short=TGBp2;
GN   ORFNames=ORF3;
OS   White clover mosaic virus (strain M) (WCMV).
OC   Viruses; Riboviria; Orthornavirae; Kitrinoviricota; Alsuviricetes;
OC   Tymovirales; Alphaflexiviridae; Potexvirus.
OX   NCBI_TaxID=12189;
OH   NCBI_TaxID=3898; Trifolium.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=3340527; DOI=10.1093/nar/16.1.291;
RA   Forster R.L.S., Bevan M.W., Harbison S.-A., Gardner R.C.;
RT   "The complete nucleotide sequence of the potexvirus white clover mosaic
RT   virus.";
RL   Nucleic Acids Res. 16:291-303(1988).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=3341118; DOI=10.1016/0042-6822(88)90487-4;
RA   Harbison S.-A., Forster R.L.S., Guilford P.J., Gardner R.C.;
RT   "Organization and interviral homologies of the coat protein gene of white
RT   clover mosaic virus.";
RL   Virology 162:459-465(1988).
RN   [3]
RP   REVIEW.
RX   PubMed=15828680; DOI=10.1094/mpmi-18-0283;
RA   Verchot-Lubicz J.;
RT   "A new cell-to-cell transport model for Potexviruses.";
RL   Mol. Plant Microbe Interact. 18:283-290(2005).
CC   -!- FUNCTION: Plays a role in viral cell-to-cell propagation, by
CC       facilitating genome transport to neighboring plant cells through
CC       plasmosdesmata,. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Host endoplasmic reticulum membrane
CC       {ECO:0000250}.
CC   -!- MISCELLANEOUS: TGBp1, TGBp2 and TGBp3 seem to act together for cell-to-
CC       cell propagation. TGBp1 is the main movement protein that physically
CC       cross the plasmodesma with the viral genome. TGBp2 and TGBp3 would
CC       facilitate TGBp1 function.
CC   -!- SIMILARITY: Belongs to the Tymovirales TGBp2 protein family.
CC       {ECO:0000305}.
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DR   EMBL; X06728; CAA29906.1; -; Genomic_RNA.
DR   EMBL; M18920; AAA69636.1; -; Genomic_RNA.
DR   PIR; B34002; B34002.
DR   RefSeq; NP_620717.1; NC_003820.1.
DR   SMR; P09500; -.
DR   GeneID; 944399; -.
DR   KEGG; vg:944399; -.
DR   Proteomes; UP000007627; Genome.
DR   GO; GO:0044167; C:host cell endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0046740; P:transport of virus in host, cell to cell; IEA:UniProtKB-KW.
DR   InterPro; IPR001896; Plant_vir_prot.
DR   Pfam; PF01307; Plant_vir_prot; 1.
PE   3: Inferred from homology;
KW   Host endoplasmic reticulum; Host membrane; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix; Transport; Viral movement protein.
FT   CHAIN           1..116
FT                   /note="Movement protein TGB2"
FT                   /id="PRO_0000222593"
FT   TOPO_DOM        1..11
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000250"
FT   TRANSMEM        12..32
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        33..77
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000250"
FT   TRANSMEM        78..98
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        99..116
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   116 AA;  12989 MW;  68C7F41909A7421A CRC64;
     MPLTPPPNPQ KTYQIAILAL GLVLLAFVLI SDHSPKVGDH LHNLPFGGEY KDGTKSIKYF
     QRPNQHSLSK TLAKSHNTTI FLLILGLIVT LHGLHYFNNN RRVSSSLHCV LCQNKH