ID   TGB2_WCMVO              Reviewed;         117 AA.
AC   P15404;
DT   01-APR-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-APR-1990, sequence version 1.
DT   03-AUG-2022, entry version 89.
DE   RecName: Full=Movement protein TGB2;
DE   AltName: Full=13 kDa protein;
DE   AltName: Full=Triple gene block 2 protein;
DE            Short=TGBp2;
GN   ORFNames=ORF3;
OS   White clover mosaic virus (strain O) (WCMV).
OC   Viruses; Riboviria; Orthornavirae; Kitrinoviricota; Alsuviricetes;
OC   Tymovirales; Alphaflexiviridae; Potexvirus.
OX   NCBI_TaxID=12190;
OH   NCBI_TaxID=3898; Trifolium.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=2353451; DOI=10.1016/0042-6822(90)90469-8;
RA   Beck D.L., Forster R.L.S., Bevan M.W., Boxen K.A., Lowe S.C., Gardner R.C.;
RT   "Infectious transcripts and nucleotide sequence of cloned cDNA of the
RT   potexvirus white clover mosaic virus.";
RL   Virology 177:152-158(1990).
RN   [2]
RP   REVIEW.
RX   PubMed=15828680; DOI=10.1094/mpmi-18-0283;
RA   Verchot-Lubicz J.;
RT   "A new cell-to-cell transport model for Potexviruses.";
RL   Mol. Plant Microbe Interact. 18:283-290(2005).
CC   -!- FUNCTION: Plays a role in viral cell-to-cell propagation, by
CC       facilitating genome transport to neighboring plant cells through
CC       plasmosdesmata,. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Host endoplasmic reticulum membrane
CC       {ECO:0000250}.
CC   -!- MISCELLANEOUS: TGBp1, TGBp2 and TGBp3 seem to act together for cell-to-
CC       cell propagation. TGBp1 is the main movement protein that physically
CC       cross the plasmodesma with the viral genome. TGBp2 and TGBp3 would
CC       facilitate TGBp1 function.
CC   -!- SIMILARITY: Belongs to the Tymovirales TGBp2 protein family.
CC       {ECO:0000305}.
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DR   EMBL; X16636; CAA34630.1; -; Genomic_RNA.
DR   PIR; S35112; S35112.
DR   Proteomes; UP000007628; Genome.
DR   GO; GO:0044167; C:host cell endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0046740; P:transport of virus in host, cell to cell; IEA:UniProtKB-KW.
DR   InterPro; IPR001896; Plant_vir_prot.
DR   Pfam; PF01307; Plant_vir_prot; 1.
PE   3: Inferred from homology;
KW   Host endoplasmic reticulum; Host membrane; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix; Transport; Viral movement protein.
FT   CHAIN           1..117
FT                   /note="Movement protein TGB2"
FT                   /id="PRO_0000222594"
FT   TOPO_DOM        1..11
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000250"
FT   TRANSMEM        12..32
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        33..78
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000250"
FT   TRANSMEM        79..99
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        100..117
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   117 AA;  13059 MW;  F883A3C17C7C1BBF CRC64;
     MPLIPPPNPQ KTYQIAVLAL GLVLLLAFVL ISDHSPKVGD HLHNLPFGGE YKDGTKTIKY
     FQRPNQHSLS KTLAKSHNTT IFLIILGLIG TLHGLHYFSN NRRISSSLHC VLCQNKH