ID   TGB3_BNYVS              Reviewed;         132 AA.
AC   Q65676;
DT   21-SEP-2011, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   23-FEB-2022, entry version 57.
DE   RecName: Full=Movement protein TGB3;
DE   AltName: Full=15 kDa protein;
DE   AltName: Full=P15;
DE   AltName: Full=Triple gene block 3 protein;
DE            Short=TGBp3;
OS   Beet necrotic yellow vein virus (isolate Japan/S) (BNYVV).
OC   Viruses; Riboviria; Orthornavirae; Kitrinoviricota; Alsuviricetes;
OC   Hepelivirales; Benyviridae; Benyvirus.
OX   NCBI_TaxID=652670;
OH   NCBI_TaxID=343494; Beta macrocarpa (Beet) (Beta vulgaris subsp. macrocarpa).
OH   NCBI_TaxID=161934; Beta vulgaris (Sugar beet).
OH   NCBI_TaxID=3562; Spinacia oleracea (Spinach).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=8973531; DOI=10.1007/bf01718223;
RA   Saito M., Kiguchi T., Kusume T., Tamada T.;
RT   "Complete nucleotide sequence of the Japanese isolate S of beet necrotic
RT   yellow vein virus RNA and comparison with European isolates.";
RL   Arch. Virol. 141:2163-2175(1996).
RN   [2]
RP   FUNCTION.
RX   PubMed=10796018; DOI=10.1094/mpmi.2000.13.5.520;
RA   Erhardt M., Morant M., Ritzenthaler C., Stussi-Garaud C., Guilley H.,
RA   Richards K., Jonard G., Bouzoubaa S., Gilmer D.;
RT   "P42 movement protein of Beet necrotic yellow vein virus is targeted by the
RT   movement proteins P13 and P15 to punctate bodies associated with
RT   plasmodesmata.";
RL   Mol. Plant Microbe Interact. 13:520-528(2000).
RN   [3]
RP   SUBCELLULAR LOCATION.
RX   PubMed=16023167; DOI=10.1016/j.virol.2005.06.012;
RA   Erhardt M., Vetter G., Gilmer D., Bouzoubaa S., Richards K., Jonard G.,
RA   Guilley H.;
RT   "Subcellular localization of the triple gene block movement proteins of
RT   Beet necrotic yellow vein virus by electron microscopy.";
RL   Virology 340:155-166(2005).
CC   -!- FUNCTION: Participates in the transport of viral RNA to the
CC       plasmodesmata. TGBp3 most probably contains signals of plasmodesmata
CC       targeting is therefore involved in the targeting of TGBp2, and viral
CC       RNAs-TGBp1 (RNP complex), to plasmodesmata. Can gate plasmodesmata and
CC       increase their size exclusion limit (By similarity). {ECO:0000250,
CC       ECO:0000269|PubMed:10796018}.
CC   -!- SUBUNIT: Interacts with movement proteins TGB1 and TGB2. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Host cell junction, host plasmodesma
CC       {ECO:0000305}. Host endoplasmic reticulum membrane {ECO:0000305};
CC       Multi-pass membrane protein {ECO:0000305}. Note=localizes to
CC       plasmodesmata or plasmodesmata-associated membrane compartments called
CC       peripheral membrane bodies (PMBs). {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the benyvirus TGB3 movement protein family.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; D84411; BAA12344.1; -; Genomic_RNA.
DR   RefSeq; NP_612619.1; NC_003515.1.
DR   GeneID; 991086; -.
DR   KEGG; vg:991086; -.
DR   Proteomes; UP000001100; Genome.
DR   GO; GO:0044167; C:host cell endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0044219; C:host cell plasmodesma; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0046740; P:transport of virus in host, cell to cell; IEA:UniProtKB-KW.
DR   InterPro; IPR010470; BNYVV_TGB3.
DR   Pfam; PF06358; DUF1065; 1.
PE   3: Inferred from homology;
KW   Host cell junction; Host endoplasmic reticulum; Host membrane; Membrane;
KW   Reference proteome; Transmembrane; Transmembrane helix; Transport;
KW   Viral movement protein.
FT   CHAIN           1..132
FT                   /note="Movement protein TGB3"
FT                   /id="PRO_0000412277"
FT   TOPO_DOM        1..11
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        12..32
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        33..109
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        110..130
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        131..132
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   132 AA;  14665 MW;  FBFCFD4055CA5630 CRC64;
     MVLVVKVDLS NIVLYIVAGC VVVSMLYSPF FSNDVKASSY AGAVFKGSGC IMDRNSFAQF
     GSCDIPKHVA ESITKVATKE HDADIMVKRG EVTVRVVTLT ETLFIILSRL FGLAVFLFMI
     CLMSIVWFWC HR