ID   TGB3_CMVSI              Reviewed;          91 AA.
AC   Q00478;
DT   01-DEC-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-1992, sequence version 1.
DT   07-OCT-2020, entry version 60.
DE   RecName: Full=Movement protein TGBp3;
DE   AltName: Full=9.7 kDa protein;
DE   AltName: Full=Triple gene block 3 protein;
DE            Short=TGBp3;
GN   ORFNames=ORF4;
OS   Cymbidium mosaic virus (strain Singapore).
OC   Viruses; Riboviria; Orthornavirae; Kitrinoviricota; Alsuviricetes;
OC   Tymovirales; Alphaflexiviridae; Potexvirus.
OX   NCBI_TaxID=31725;
OH   NCBI_TaxID=38236; Cattleya.
OH   NCBI_TaxID=112603; Cymbidium aloifolium.
OH   NCBI_TaxID=28471; Cymbidium hybrid cultivar.
OH   NCBI_TaxID=160533; Cymbidium iridioides.
OH   NCBI_TaxID=38234; Epidendrum.
OH   NCBI_TaxID=123155; Laelia.
OH   NCBI_TaxID=45173; Oncidium.
OH   NCBI_TaxID=120015; Phaius tancarvilleae (Nun's hood orchid) (Greater swamp orchid).
OH   NCBI_TaxID=36459; Phalaenopsis.
OH   NCBI_TaxID=141750; Pholidota imbricata.
OH   NCBI_TaxID=38198; Vanda.
OH   NCBI_TaxID=78858; Zygopetalum.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=1581564; DOI=10.1007/bf00019225;
RA   Neo K.K., Wong S.M., Wu M.;
RT   "Nucleotide sequences of the two ORFs upstream to the coat protein gene of
RT   cymbidium mosaic virus.";
RL   Plant Mol. Biol. 18:1027-1029(1992).
RN   [2]
RP   REVIEW.
RX   PubMed=15828680; DOI=10.1094/mpmi-18-0283;
RA   Verchot-Lubicz J.;
RT   "A new cell-to-cell transport model for Potexviruses.";
RL   Mol. Plant Microbe Interact. 18:283-290(2005).
CC   -!- FUNCTION: Plays a role in viral cell-to-cell propagation, by
CC       facilitating genome transport to neighboring plant cells through
CC       plasmosdesmata. May induce the formation of granular vesicles derived
CC       from the Endoplasmic reticulum, which align on actin filaments (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Host endoplasmic reticulum membrane
CC       {ECO:0000250}.
CC   -!- MISCELLANEOUS: TGBp1, TGBp2 and TGBp3 seem to act together for cell-to-
CC       cell propagation. TGBp1 is the main movement protein that physically
CC       cross the plasmodesma with the viral genome. TGBp2 and TGBp3 would
CC       facilitate TGBp1 function.
CC   -!- SIMILARITY: Belongs to the Tymovirales TGBp3 protein family.
CC       {ECO:0000305}.
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DR   EMBL; X62663; CAA44530.1; -; Genomic_RNA.
DR   PIR; S20927; WMWG10.
DR   SMR; Q00478; -.
DR   GO; GO:0044167; C:host cell endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0046740; P:transport of virus in host, cell to cell; IEA:UniProtKB-KW.
DR   InterPro; IPR003411; TGBp3.
DR   Pfam; PF02495; TGBp3; 1.
PE   3: Inferred from homology;
KW   Host endoplasmic reticulum; Host membrane; Membrane; Transmembrane;
KW   Transmembrane helix; Transport; Viral movement protein.
FT   CHAIN           1..91
FT                   /note="Movement protein TGBp3"
FT                   /id="PRO_0000222600"
FT   TOPO_DOM        1..23
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        24..46
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        47..91
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   91 AA;  9666 MW;  15E1A8521532B011 CRC64;
     MLGTRNIPTT SGLPLPPPSS SLSAYIFPTI LAIIFAVFAL VAIHITTPEP FCTIHIDGAS
     ITITNCPDPA AILNKVAIGP WRGLSYHNNL K