TGB3_CVB
ID TGB3_CVB Reviewed; 64 AA.
AC P37990;
DT 01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-1994, sequence version 1.
DT 07-OCT-2020, entry version 54.
DE RecName: Full=Movement protein TGBp3;
DE AltName: Full=7 kDa protein;
DE AltName: Full=Triple gene block 3 protein;
DE Short=TGBp3;
GN ORFNames=ORF4;
OS Chrysanthemum virus B (CVB).
OC Viruses; Riboviria; Orthornavirae; Kitrinoviricota; Alsuviricetes;
OC Tymovirales; Betaflexiviridae; Quinvirinae; Carlavirus.
OX NCBI_TaxID=12165;
OH NCBI_TaxID=41568; Chrysanthemum morifolium (Florist's daisy) (Dendranthema grandiflorum).
OH NCBI_TaxID=109564; Gynura.
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX PubMed=1919520; DOI=10.1099/0022-1317-72-10-2333;
RA Levay K., Zavriev S.;
RT "Nucleotide sequence and gene organization of the 3'-terminal region of
RT chrysanthemum virus B genomic RNA.";
RL J. Gen. Virol. 72:2333-2337(1991).
CC -!- FUNCTION: Plays a role in viral cell-to-cell propagation, by
CC facilitating genome transport to neighboring plant cells through
CC plasmosdesmata. May induce the formation of granular vesicles derived
CC from the Endoplasmic reticulum, which align on actin filaments (By
CC similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Host endoplasmic reticulum membrane
CC {ECO:0000250}.
CC -!- MISCELLANEOUS: TGBp1, TGBp2 and TGBp3 seem to act together for cell-to-
CC cell propagation. TGBp1 is the main movement protein that physically
CC cross the plasmodesma with the viral genome. TGBp2 and TGBp3 would
CC facilitate TGBp1 function.
CC -!- SIMILARITY: Belongs to the Tymovirales TGBp3 protein family.
CC {ECO:0000305}.
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DR EMBL; S60150; AAB20079.1; -; Genomic_RNA.
DR PIR; JQ1249; JQ1249.
DR GO; GO:0044167; C:host cell endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0046740; P:transport of virus in host, cell to cell; IEA:UniProtKB-KW.
DR InterPro; IPR003411; TGBp3.
DR Pfam; PF02495; TGBp3; 1.
PE 3: Inferred from homology;
KW Host endoplasmic reticulum; Host membrane; Membrane; Transmembrane;
KW Transmembrane helix; Transport; Viral movement protein.
FT CHAIN 1..64
FT /note="Movement protein TGBp3"
FT /id="PRO_0000222612"
FT TOPO_DOM 1..7
FT /note="Lumenal"
FT /evidence="ECO:0000255"
FT TRANSMEM 8..28
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 29..64
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
SQ SEQUENCE 64 AA; 6984 MW; 37E653F0BE53C768 CRC64;
MSLSYLDLLL AFGCVLAVSV IVNCFLVSHN NCVIEITGEA VRISGCTFDR TFVELVKGLK
PARH