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TGB3_FXMV
ID   TGB3_FXMV               Reviewed;          52 AA.
AC   P22171; B1NLP7;
DT   01-AUG-1991, integrated into UniProtKB/Swiss-Prot.
DT   28-JUN-2011, sequence version 2.
DT   07-OCT-2020, entry version 64.
DE   RecName: Full=Movement protein TGBp3;
DE   AltName: Full=7 kDa protein;
DE   AltName: Full=Triple gene block 3 protein;
DE            Short=TGBp3;
GN   ORFNames=ORF4;
OS   Foxtail mosaic virus.
OC   Viruses; Riboviria; Orthornavirae; Kitrinoviricota; Alsuviricetes;
OC   Tymovirales; Alphaflexiviridae; Potexvirus.
OX   NCBI_TaxID=12179;
OH   NCBI_TaxID=4555; Setaria italica (Foxtail millet) (Panicum italicum).
OH   NCBI_TaxID=4556; Setaria viridis (Green bristlegrass) (Setaria italica subsp. viridis).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=1840610; DOI=10.1099/0022-1317-72-9-2173;
RA   Bancroft J.B., Rouleau M., Johnston R., Prins L., Mackie G.A.;
RT   "The entire nucleotide sequence of foxtail mosaic virus RNA.";
RL   J. Gen. Virol. 72:2173-2181(1991).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=17955161; DOI=10.1007/s00705-007-1057-3;
RA   Bruun-Rasmussen M., Madsen C.T., Johansen E., Albrechtsen M.;
RT   "Revised sequence of foxtail mosaic virus reveals a triple gene block
RT   structure similar to potato virus X.";
RL   Arch. Virol. 153:223-226(2008).
RN   [3]
RP   REVIEW.
RX   PubMed=15828680; DOI=10.1094/mpmi-18-0283;
RA   Verchot-Lubicz J.;
RT   "A new cell-to-cell transport model for Potexviruses.";
RL   Mol. Plant Microbe Interact. 18:283-290(2005).
CC   -!- FUNCTION: Plays a role in viral cell-to-cell propagation, by
CC       facilitating genome transport to neighboring plant cells through
CC       plasmosdesmata. May induce the formation of granular vesicles derived
CC       from the Endoplasmic reticulum, which align on actin filaments (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Host endoplasmic reticulum membrane
CC       {ECO:0000250}.
CC   -!- MISCELLANEOUS: TGBp1, TGBp2 and TGBp3 seem to act together for cell-to-
CC       cell propagation. TGBp1 is the main movement protein that physically
CC       cross the plasmodesma with the viral genome. TGBp2 and TGBp3 would
CC       facilitate TGBp1 function.
CC   -!- SIMILARITY: Belongs to the Tymovirales TGBp3 protein family.
CC       {ECO:0000305}.
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DR   EMBL; M62730; AAA43829.1; -; Genomic_RNA.
DR   EMBL; EF630359; ABW25051.1; -; Genomic_RNA.
DR   EMBL; EF630360; ABW25057.1; -; Genomic_RNA.
DR   PIR; JQ1261; JQ1261.
DR   RefSeq; NP_040991.1; NC_001483.1.
DR   GeneID; 1494012; -.
DR   KEGG; vg:1494012; -.
DR   Proteomes; UP000008623; Genome.
DR   GO; GO:0044167; C:host cell endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0046740; P:transport of virus in host, cell to cell; IEA:UniProtKB-KW.
DR   InterPro; IPR003411; TGBp3.
DR   Pfam; PF02495; TGBp3; 1.
PE   3: Inferred from homology;
KW   Host endoplasmic reticulum; Host membrane; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix; Transport; Viral movement protein.
FT   CHAIN           1..52
FT                   /note="Movement protein TGBp3"
FT                   /id="PRO_0000222602"
FT   TOPO_DOM        1..3
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        4..21
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        22..52
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   CONFLICT        15
FT                   /note="L -> I (in Ref. 1; AAA43829)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   52 AA;  5849 MW;  0A66FEACDDF6934E CRC64;
     MHESHLVVIL ALLLLALWCL STRPVQPSCH VEINGHSIIV TGNCWHSTQR PH
 
 
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