ID   TGB3_ICRSV              Reviewed;          60 AA.
AC   Q918W0;
DT   02-NOV-2010, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2001, sequence version 1.
DT   29-SEP-2021, entry version 33.
DE   RecName: Full=Movement protein TGBp3;
DE   AltName: Full=Triple gene block 3 protein;
DE            Short=TGBp3;
GN   ORFNames=ORF4;
OS   Indian citrus ringspot virus (isolate Kinnow mandarin/India/K1/1996)
OS   (ICRSV).
OC   Viruses; Riboviria; Orthornavirae; Kitrinoviricota; Alsuviricetes;
OC   Tymovirales; Alphaflexiviridae; Potexvirus; Mandarivirus.
OX   NCBI_TaxID=651357;
OH   NCBI_TaxID=2706; Citrus.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=11043949; DOI=10.1007/s007050070064;
RA   Rustici G., Accotto G.P., Noris E., Masenga V., Luisoni E., Milne R.G.;
RT   "Indian citrus ringspot virus: a proposed new species with some affinities
RT   to potex-, carla-, fovea- and allexiviruses.";
RL   Arch. Virol. 145:1895-1908(2000).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=12417955; DOI=10.1007/s00705-002-0875-6;
RA   Rustici G., Milne R.G., Accotto G.P.;
RT   "Nucleotide sequence, genome organisation and phylogenetic analysis of
RT   Indian citrus ringspot virus.";
RL   Arch. Virol. 147:2215-2224(2002).
CC   -!- FUNCTION: Plays a role in viral cell-to-cell propagation, by
CC       facilitating genome transport to neighboring plant cells through
CC       plasmosdesmata. May induce the formation of granular vesicles derived
CC       from the Endoplasmic reticulum, which align on actin filaments (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Host endoplasmic reticulum membrane
CC       {ECO:0000250}.
CC   -!- MISCELLANEOUS: TGBp1, TGBp2 and TGBp3 seem to act together for cell-to-
CC       cell propagation. TGBp1 is the main movement protein that physically
CC       cross the plasmodesma with the viral genome. TGBp2 and TGBp3 would
CC       facilitate TGBp1 function.
CC   -!- SIMILARITY: Belongs to the Tymovirales TGBp3 protein family.
CC       {ECO:0000305}.
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DR   EMBL; AF406744; AAK97525.1; -; Genomic_RNA.
DR   RefSeq; NP_203556.1; NC_003093.1.
DR   GeneID; 922106; -.
DR   KEGG; vg:922106; -.
DR   Proteomes; UP000000394; Genome.
DR   GO; GO:0044167; C:host cell endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0046740; P:transport of virus in host, cell to cell; IEA:UniProtKB-KW.
DR   InterPro; IPR003411; TGBp3.
DR   Pfam; PF02495; TGBp3; 1.
PE   3: Inferred from homology;
KW   Host endoplasmic reticulum; Host membrane; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix; Transport; Viral movement protein.
FT   CHAIN           1..60
FT                   /note="Movement protein TGBp3"
FT                   /id="PRO_0000401081"
FT   TOPO_DOM        1..6
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        7..23
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        24..60
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   60 AA;  6389 MW;  79BF5E12B0534B9D CRC64;
     MHYIDWVILL TFAAALIVCL TPKPEPCIIT VSGASATVSN CPNPELLTDL VKALKPAKPV