ID   TGB3_LOLV               Reviewed;          72 AA.
AC   B1PS79;
DT   02-NOV-2010, integrated into UniProtKB/Swiss-Prot.
DT   29-APR-2008, sequence version 1.
DT   07-OCT-2020, entry version 22.
DE   RecName: Full=Movement protein TGBp3;
DE   AltName: Full=Triple gene block 3 protein;
DE            Short=TGBp3;
GN   Name=ORF4;
OS   Lolium latent virus (isolate Lolium/USA/US1/-) (LoLV).
OC   Viruses; Riboviria; Orthornavirae; Kitrinoviricota; Alsuviricetes;
OC   Tymovirales; Alphaflexiviridae; Lolavirus.
OX   NCBI_TaxID=686945;
OH   NCBI_TaxID=480553; Lolium multiflorum x Lolium perenne.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RA   Vaira A.M.V., Maroon-Lango C.J., Hammond J.;
RT   "Molecular characterization of Lolium latent virus, proposed type member of
RT   a new genus in the family Flexiviridae.";
RL   Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays a role in viral cell-to-cell propagation, by
CC       facilitating genome transport to neighboring plant cells through
CC       plasmosdesmata. May induce the formation of granular vesicles derived
CC       from the Endoplasmic reticulum, which align on actin filaments (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Host endoplasmic reticulum membrane
CC       {ECO:0000250}.
CC   -!- MISCELLANEOUS: TGBp1, TGBp2 and TGBp3 seem to act together for cell-to-
CC       cell propagation. TGBp1 is the main movement protein that physically
CC       cross the plasmodesma with the viral genome. TGBp2 and TGBp3 would
CC       facilitate TGBp1 function.
CC   -!- SIMILARITY: Belongs to the Tymovirales TGBp3 protein family.
CC       {ECO:0000305}.
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DR   EMBL; EU489641; ACA53377.1; -; Genomic_RNA.
DR   RefSeq; YP_001718502.1; NC_010434.1.
DR   GeneID; 6000099; -.
DR   KEGG; vg:6000099; -.
DR   Proteomes; UP000008689; Genome.
DR   GO; GO:0044167; C:host cell endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0046740; P:transport of virus in host, cell to cell; IEA:UniProtKB-KW.
DR   InterPro; IPR003411; TGBp3.
DR   Pfam; PF02495; TGBp3; 1.
PE   3: Inferred from homology;
KW   Host endoplasmic reticulum; Host membrane; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix; Transport; Viral movement protein.
FT   CHAIN           1..72
FT                   /note="Movement protein TGBp3"
FT                   /id="PRO_0000401076"
FT   TOPO_DOM        1..2
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        3..23
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        24..72
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   72 AA;  7542 MW;  694BA807A7463CA9 CRC64;
     MSLSFSLIVF AVGVAVSIGV LTLTTQQSSS YCLILVDGAK AVVEGCHLRQ DIPAILSELK
     PASSPFNPLF CS