TGB3_NMV
ID TGB3_NMV Reviewed; 100 AA.
AC P15098;
DT 01-APR-1990, integrated into UniProtKB/Swiss-Prot.
DT 01-APR-1990, sequence version 1.
DT 23-FEB-2022, entry version 70.
DE RecName: Full=Movement protein TGBp3;
DE AltName: Full=7 kDa protein;
DE AltName: Full=Triple gene block 3 protein;
DE Short=TGBp3;
GN ORFNames=ORF4;
OS Narcissus mosaic virus (NMV).
OC Viruses; Riboviria; Orthornavirae; Kitrinoviricota; Alsuviricetes;
OC Tymovirales; Alphaflexiviridae; Potexvirus.
OX NCBI_TaxID=12180;
OH NCBI_TaxID=39639; Narcissus pseudonarcissus (Daffodil).
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX PubMed=2732689; DOI=10.1099/0022-1317-70-2-267;
RA Zuidema D., Linthorst H.J.M., Huisman M.J., Asjes C.J., Bol J.F.;
RT "Nucleotide sequence of narcissus mosaic virus RNA.";
RL J. Gen. Virol. 70:267-276(1989).
RN [2]
RP REVIEW.
RX PubMed=15828680; DOI=10.1094/mpmi-18-0283;
RA Verchot-Lubicz J.;
RT "A new cell-to-cell transport model for Potexviruses.";
RL Mol. Plant Microbe Interact. 18:283-290(2005).
CC -!- FUNCTION: Plays a role in viral cell-to-cell propagation, by
CC facilitating genome transport to neighboring plant cells through
CC plasmosdesmata. May induce the formation of granular vesicles derived
CC from the Endoplasmic reticulum, which align on actin filaments (By
CC similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Host endoplasmic reticulum membrane
CC {ECO:0000250}.
CC -!- MISCELLANEOUS: TGBp1, TGBp2 and TGBp3 seem to act together for cell-to-
CC cell propagation. TGBp1 is the main movement protein that physically
CC cross the plasmodesma with the viral genome. TGBp2 and TGBp3 would
CC facilitate TGBp1 function.
CC -!- SIMILARITY: Belongs to the Tymovirales TGBp3 protein family.
CC {ECO:0000305}.
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DR EMBL; D13747; BAA02894.1; -; Genomic_RNA.
DR PIR; JT0473; WMWGN3.
DR RefSeq; NP_040781.1; NC_001441.1.
DR GeneID; 1494017; -.
DR KEGG; vg:1494017; -.
DR Proteomes; UP000008865; Genome.
DR GO; GO:0044167; C:host cell endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0046740; P:transport of virus in host, cell to cell; IEA:UniProtKB-KW.
DR InterPro; IPR003411; TGBp3.
DR Pfam; PF02495; TGBp3; 1.
PE 3: Inferred from homology;
KW Host endoplasmic reticulum; Host membrane; Membrane; Reference proteome;
KW Transmembrane; Transmembrane helix; Transport; Viral movement protein.
FT CHAIN 1..100
FT /note="Movement protein TGBp3"
FT /id="PRO_0000222603"
FT TOPO_DOM 1..41
FT /note="Lumenal"
FT /evidence="ECO:0000255"
FT TRANSMEM 42..59
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 60..100
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
SQ SEQUENCE 100 AA; 11059 MW; 17423F1D710E2173 CRC64;
MQTAPREYST SGPTAVLAPT TNTQHYAPYS LYRFLSSHKL DLLLGIALLV FLYVITAAPK
EVCQVVITGE SVVIRNCQQP DRILANLNLS PWNGVKFPLL