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TGB3_P1AMV
ID   TGB3_P1AMV              Reviewed;         121 AA.
AC   Q07520;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   02-JUN-2021, entry version 60.
DE   RecName: Full=Movement protein TGBp3;
DE   AltName: Full=13 kDa protein;
DE   AltName: Full=Triple gene block 3 protein;
DE            Short=TGBp3;
GN   ORFNames=ORF4;
OS   Plantago asiatica mosaic potexvirus (P1AMV).
OC   Viruses; Riboviria; Orthornavirae; Kitrinoviricota; Alsuviricetes;
OC   Tymovirales; Alphaflexiviridae; Potexvirus.
OX   NCBI_TaxID=28354;
OH   NCBI_TaxID=197796; Plantago asiatica.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=8113746; DOI=10.1099/0022-1317-75-2-259;
RA   Solovyev A.G., Novikov V.K., Merits A., Savenkov E.I., Zelenina D.A.,
RA   Tyulkina L.G., Morozov S.Y.;
RT   "Genome characterization and taxonomy of Plantago asiatica mosaic
RT   potexvirus.";
RL   J. Gen. Virol. 75:259-267(1994).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=8477237;
RA   Solovyev A.G., Novikov V.K., Morozov S.I., Kagramanov V.N., Atabekov I.G.;
RT   "Primary structure of the triple block RNA genes of the Plantago asiatica
RT   mosaic virus.";
RL   Dokl. Akad. Nauk 328:625-628(1993).
CC   -!- FUNCTION: Plays a role in viral cell-to-cell propagation, by
CC       facilitating genome transport to neighboring plant cells through
CC       plasmosdesmata. May induce the formation of granular vesicles derived
CC       from the Endoplasmic reticulum, which align on actin filaments (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Host endoplasmic reticulum membrane
CC       {ECO:0000250}.
CC   -!- MISCELLANEOUS: TGBp1, TGBp2 and TGBp3 seem to act together for cell-to-
CC       cell propagation. TGBp1 is the main movement protein that physically
CC       cross the plasmodesma with the viral genome. TGBp2 and TGBp3 would
CC       facilitate TGBp1 function.
CC   -!- SIMILARITY: Belongs to the Tymovirales TGBp3 protein family.
CC       {ECO:0000305}.
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DR   EMBL; Z21647; CAA79764.1; -; Genomic_RNA.
DR   EMBL; S61526; AAB26350.1; -; Genomic_RNA.
DR   PIR; S34233; S34233.
DR   RefSeq; NP_620839.1; NC_003849.1.
DR   GeneID; 944431; -.
DR   KEGG; vg:944431; -.
DR   Proteomes; UP000009190; Genome.
DR   GO; GO:0044167; C:host cell endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0046740; P:transport of virus in host, cell to cell; IEA:UniProtKB-KW.
DR   InterPro; IPR003411; TGBp3.
DR   Pfam; PF02495; TGBp3; 1.
PE   3: Inferred from homology;
KW   Host endoplasmic reticulum; Host membrane; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix; Transport; Viral movement protein.
FT   CHAIN           1..121
FT                   /note="Movement protein TGBp3"
FT                   /id="PRO_0000222618"
FT   TOPO_DOM        1..43
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        44..64
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        65..121
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   REGION          1..40
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        7..40
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   121 AA;  12700 MW;  6A57ED9FF22E76E7 CRC64;
     MHYPTEADTS TGPNPSATSA PVRPRHVTPS LSPSSSSSPS PDSFYYFLAA AVILTAALAA
     ALLTPNPGCT IVITGHTTII QGSCPIPPQL VLAAHPRGLS LEQYLKFTNT LPDGSQHRSH
     R
 
 
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