ID   TGB3_PVMR               Reviewed;          63 AA.
AC   P17528;
DT   01-AUG-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1990, sequence version 1.
DT   07-OCT-2020, entry version 77.
DE   RecName: Full=Movement protein TGBp3;
DE   AltName: Full=7 kDa protein;
DE   AltName: Full=Triple gene block 3 protein;
DE            Short=TGBp3;
GN   ORFNames=ORF4;
OS   Potato virus M (strain Russian) (PVM).
OC   Viruses; Riboviria; Orthornavirae; Kitrinoviricota; Alsuviricetes;
OC   Tymovirales; Betaflexiviridae; Quinvirinae; Carlavirus.
OX   NCBI_TaxID=12168;
OH   NCBI_TaxID=4113; Solanum tuberosum (Potato).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=2738581; DOI=10.1099/0022-1317-70-7-1861;
RA   Rupasov V.V., Morozov S.Y., Kanyuka K.V., Zavriev S.K.;
RT   "Partial nucleotide sequence of potato virus M RNA shows similarities to
RT   protexviruses in gene arrangement and the encoded amino acid sequences.";
RL   J. Gen. Virol. 70:1861-1869(1989).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=1990070; DOI=10.1099/0022-1317-72-1-9;
RA   Zavriev S.K., Kanyuka K.V., Levay K.E.;
RT   "The genome organization of potato virus M RNA.";
RL   J. Gen. Virol. 72:9-14(1991).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=1944258;
RA   Zavriev S.K., Kaniuka K.V., Levai K.E.;
RT   "Complete nucleotide sequence of genomic RNA of the potato M-virus.";
RL   Mol. Biol. (Mosk.) 25:761-769(1991).
CC   -!- FUNCTION: Plays a role in viral cell-to-cell propagation, by
CC       facilitating genome transport to neighboring plant cells through
CC       plasmosdesmata. May induce the formation of granular vesicles derived
CC       from the Endoplasmic reticulum, which align on actin filaments (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Host endoplasmic reticulum membrane
CC       {ECO:0000250}.
CC   -!- MISCELLANEOUS: TGBp1, TGBp2 and TGBp3 seem to act together for cell-to-
CC       cell propagation. TGBp1 is the main movement protein that physically
CC       cross the plasmodesma with the viral genome. TGBp2 and TGBp3 would
CC       facilitate TGBp1 function.
CC   -!- SIMILARITY: Belongs to the Tymovirales TGBp3 protein family.
CC       {ECO:0000305}.
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DR   EMBL; D14449; BAA03342.1; -; Genomic_RNA.
DR   PIR; PN0004; WMVYP3.
DR   RefSeq; NP_056770.1; NC_001361.2.
DR   GeneID; 1493992; -.
DR   KEGG; vg:1493992; -.
DR   Proteomes; UP000000677; Genome.
DR   GO; GO:0044167; C:host cell endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0046740; P:transport of virus in host, cell to cell; IEA:UniProtKB-KW.
DR   InterPro; IPR003411; TGBp3.
DR   Pfam; PF02495; TGBp3; 1.
PE   3: Inferred from homology;
KW   Host endoplasmic reticulum; Host membrane; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix; Transport; Viral movement protein.
FT   CHAIN           1..63
FT                   /note="Movement protein TGBp3"
FT                   /id="PRO_0000222616"
FT   TRANSMEM        1..21
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        22..63
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   63 AA;  6747 MW;  0B755CDD8C96CA1B CRC64;
     MIVYVLVGLS AFCIVLYLIS QGQSDCVVLI TGESVRVQGC RIDGEFGSVL SKLKPFGCGS
     FRS