TGRI3_DICDI
ID TGRI3_DICDI Reviewed; 852 AA.
AC Q54RE1;
DT 22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT 22-SEP-2009, sequence version 2.
DT 25-MAY-2022, entry version 66.
DE RecName: Full=Tiger protein I3;
DE AltName: Full=Transmembrane, IPT, Ig, E-set, Repeat protein I3;
DE Flags: Precursor;
GN Name=tgrI3; ORFNames=DDB_G0283249;
OS Dictyostelium discoideum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=15875012; DOI=10.1038/nature03481;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
CC -!- SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
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DR EMBL; AAFI02000051; EAL65863.2; -; Genomic_DNA.
DR RefSeq; XP_639204.2; XM_634112.2.
DR AlphaFoldDB; Q54RE1; -.
DR PaxDb; Q54RE1; -.
DR PRIDE; Q54RE1; -.
DR EnsemblProtists; EAL65863; EAL65863; DDB_G0283249.
DR GeneID; 8623978; -.
DR KEGG; ddi:DDB_G0283249; -.
DR dictyBase; DDB_G0283249; tgrI3.
DR HOGENOM; CLU_009950_0_0_1; -.
DR InParanoid; Q54RE1; -.
DR OMA; IWENHET; -.
DR PhylomeDB; Q54RE1; -.
DR PRO; PR:Q54RE1; -.
DR Proteomes; UP000002195; Chromosome 4.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR Gene3D; 2.60.40.10; -; 1.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR002909; IPT_dom.
DR Pfam; PF01833; TIG; 1.
DR SUPFAM; SSF81296; SSF81296; 1.
PE 3: Inferred from homology;
KW Glycoprotein; Membrane; Reference proteome; Signal; Transmembrane;
KW Transmembrane helix.
FT SIGNAL 1..18
FT /evidence="ECO:0000255"
FT CHAIN 19..852
FT /note="Tiger protein I3"
FT /id="PRO_0000384055"
FT TOPO_DOM 19..830
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 831..851
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 852
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT DOMAIN 290..367
FT /note="IPT/TIG"
FT CARBOHYD 31
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 47
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 67
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 97
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 129
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 201
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 215
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 228
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 260
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 323
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 352
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 356
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 404
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 441
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 476
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 483
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 501
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 512
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 574
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 592
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 635
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 658
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 661
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 679
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 680
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 723
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 757
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 761
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 773
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 785
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 800
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 852 AA; 96258 MW; DD78916AEA5105D3 CRC64;
MKILLFFILF YLFSFSISYD EVIPLGYESH NDSLVIRYRE IENYYTNISF LWKGKSRYDM
SFNCVLNNTI RTCTLPVKES DHAQMYSEEI SACTENNGTF KMCGYDLPLF YFPSPLLISE
FKPKTRGGNT TLSGYYLELK ERIYVQFENS YRKDQFFYSG YVYLIPGVFQ SKTPDRINLI
LKVYPGCGYR TIIWENHETL NFTYQEPNIE KIDINQSFLD ITGTNFYNQS IFVSVKIDNN
IIDPNDIISV DFEIIKLKFN YSDPFSSKFN VQVGCCDYWS SQFQITYPPI PSIVNSIPKL
KGGLLIINGN RLTSSPSSSN NNNISVTVGD SICSIVSSSS NEIKCNLQPL SNSTFNNSSP
IAVSINDVVN TNTLLLIYDT PYITTFSQVN DEIHIIGGCF GNINSTQIHI NDKQVFGQIK
SINNDETDLI LKIQNQIYNF NISIESNSIK SNGINVDVEM YARINEIPLV SNKLINFTLF
YVNSSNINLI PTIKIINEKS NQTSKSISTN VNESVVSCSF LIENNCGIIN YEIEIGNQIY
QSSFSYESPL INKCNLNSNE IVTCIGKGFV NKYNETSIFI SGQSIALSKE INNSIYESIS
FQMNDEYNIL GELYLNVCGL LSNKVNINTF PIFKNVSIPN LFDTNGGNII IIGKYLNNNT
NFTIECNGEQ IIEKECKLNN SSTSLECYIK LNGPNGKTCK LLFNNDNNIV STFSFIYKSP
SINQTSIINL KQGGILTIIG NDFYYPIDKV TIIGNGNGSG NSSLNCNEAK YINDTMITCF
IQATNYTFNN IKNGEMIFIN VSTNGKSGIS KVFKYLTQSD DVHQYSDARN IFQNLLLSIL
IIIIISLFIS NI
