TGRO1_DICDI
ID TGRO1_DICDI Reviewed; 887 AA.
AC Q55GI8;
DT 22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT 22-SEP-2009, sequence version 2.
DT 25-MAY-2022, entry version 67.
DE RecName: Full=Tiger protein O1;
DE AltName: Full=Transmembrane, IPT, Ig, E-set, Repeat protein O1;
DE Flags: Precursor;
GN Name=tgrO1; ORFNames=DDB_G0268490;
OS Dictyostelium discoideum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=15875012; DOI=10.1038/nature03481;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
CC -!- SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
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DR EMBL; AAFI02000003; EAL73698.2; -; Genomic_DNA.
DR RefSeq; XP_647196.2; XM_642104.2.
DR AlphaFoldDB; Q55GI8; -.
DR STRING; 44689.DDB0304789; -.
DR PaxDb; Q55GI8; -.
DR PRIDE; Q55GI8; -.
DR EnsemblProtists; EAL73698; EAL73698; DDB_G0268490.
DR GeneID; 8616000; -.
DR KEGG; ddi:DDB_G0268490; -.
DR dictyBase; DDB_G0268490; tgrO1.
DR eggNOG; ENOG502SXB7; Eukaryota.
DR HOGENOM; CLU_009950_0_0_1; -.
DR InParanoid; Q55GI8; -.
DR PhylomeDB; Q55GI8; -.
DR PRO; PR:Q55GI8; -.
DR Proteomes; UP000002195; Chromosome 1.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR002909; IPT_dom.
DR Pfam; PF01833; TIG; 2.
DR SUPFAM; SSF81296; SSF81296; 1.
PE 3: Inferred from homology;
KW Glycoprotein; Membrane; Reference proteome; Repeat; Signal; Transmembrane;
KW Transmembrane helix.
FT SIGNAL 1..21
FT /evidence="ECO:0000255"
FT CHAIN 22..887
FT /note="Tiger protein O1"
FT /id="PRO_0000384054"
FT TOPO_DOM 22..845
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 846..866
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 867..887
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT DOMAIN 277..365
FT /note="IPT/TIG 1"
FT DOMAIN 710..767
FT /note="IPT/TIG 2"
FT REGION 811..835
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 814..835
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CARBOHYD 32
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 70
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 186
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 207
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 219
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 259
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 297
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 314
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 325
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 338
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 354
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 393
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 431
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 588
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 629
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 652
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 687
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 710
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 720
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 730
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 775
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 788
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 811
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 816
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 887 AA; 99445 MW; 5B62213A7EFEF89B CRC64;
MEKKLLIIVI VFLFSTIQVF CRIDDKTFVI SNETYLSYHF PVDSEYFSSL NFEHYEGPSF
QLDFECITFN GTICFSQIYP EIKKKIYGTS ISYSTQKTYK LDQELFPTPI VSSPFQPPTK
GGISILKGTF LTFSEKTFYQ VIYPKKQKIF ILDSESLSFD ATNFKVNCPP GCGYQIIKWD
NGNLFNFSYS NPSISVVKIN PSNIIVNGSD FCDSSYSSNI TIDGVIIPNS NYEKDEDSIV
IIYTQQHTIK SLMKIETSNV TSVEIEIVFK PEPLLINSVP YSKGGLLILE GLRLSSNTTN
KNNNNNNIII KIGNITCSNA ISISNDSITC NLNPGFNNKS VTLNNLPVSV TINNITNENK
LLFNYGIVKL NPNKYSLPDR VLQLNGDCLG NSNGTIVYLN GKETLLNDLK INNQETTLSF
KIPDEFKSKL NVSIKVNDIL SNEIQIDISF YASHSNEQPS TNGNTNIIFT LYNIKSENYN
KIPSIIIIPE QIVINGVSVN SPTNQDVHSY SFLIPAGCGK KDIQIIIGSQ SCLSSITYFE
PIIKNCLVSG FDGTNGNIIC DGSFGNKDYL IKSSVLFSND EIIPPSINST TFSFPLISGY
HSDDLIFQMC GVQSKPFKLN ISPSLKGINQ SQMETLGGKF YILGEFFSAN INCSVFCNDK
EYEKKFENSK TISFDLQIPG PNDITCNYTF DNGKNTGDFK IEYPLPLIEN TSSINVNGGN
LTIYGKNFYN VSNIKVEVDN QLKCNKIEFI NLNSLTCFLP PFIETLFNDQ KLLLNSSTTI
FSKKLLLNVT FESKTWSGYI FQYSKEEIKN NDTSENSTND ILNHEKNNNN QKDGSSLSKK
SIILLSILLP SFIILIVSLA IVILVIKRNK TKHSKNMSSK EKELMKQ
