TGT2_ARATH
ID TGT2_ARATH Reviewed; 575 AA.
AC Q39117; O48592; Q8LBM5;
DT 30-NOV-2010, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 25-MAY-2022, entry version 140.
DE RecName: Full=Trihelix transcription factor GT-2;
DE AltName: Full=Trihelix DNA-binding protein GT-2;
GN Name=GT-2; OrderedLocusNames=At1g76890; ORFNames=F7O12.6;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=8219069; DOI=10.1007/bf00029009;
RA Kuhn R.M., Caspar T., Dehesh K., Quail P.H.;
RT "DNA binding factor GT-2 from Arabidopsis.";
RL Plant Mol. Biol. 23:337-348(1993).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=9501260; DOI=10.1073/pnas.95.6.3318;
RA Smalle J.A.H., Kurepa J., Haegman M., Gielen J., Van Montagu M.,
RA Van Der Straeten D.;
RT "The trihelix DNA-binding motif in higher plants is not restricted to the
RT transcription factors GT-1 and GT-2.";
RL Proc. Natl. Acad. Sci. U.S.A. 95:3318-3322(1998).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Bautista V.R., Kim C.J., Chen H., Wu S.Y., De Los Reyes C., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Probable transcription factor that binds specific DNA
CC sequence. {ECO:0000250}.
CC -!- INTERACTION:
CC Q39117; O23160: MYB73; NbExp=3; IntAct=EBI-25517023, EBI-25506855;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAM64675.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR EMBL; X72780; CAA51289.1; -; Genomic_DNA.
DR EMBL; AJ003217; CAA05997.1; -; Genomic_DNA.
DR EMBL; AC079283; AAG51145.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE35899.1; -; Genomic_DNA.
DR EMBL; BT030363; ABO38776.1; -; mRNA.
DR EMBL; AY087117; AAM64675.1; ALT_INIT; mRNA.
DR PIR; S39484; S39484.
DR RefSeq; NP_177815.1; NM_106340.4.
DR AlphaFoldDB; Q39117; -.
DR SMR; Q39117; -.
DR BioGRID; 29243; 1.
DR IntAct; Q39117; 1.
DR STRING; 3702.AT1G76890.2; -.
DR iPTMnet; Q39117; -.
DR PaxDb; Q39117; -.
DR PRIDE; Q39117; -.
DR ProteomicsDB; 234269; -.
DR EnsemblPlants; AT1G76890.2; AT1G76890.2; AT1G76890.
DR GeneID; 844024; -.
DR Gramene; AT1G76890.2; AT1G76890.2; AT1G76890.
DR KEGG; ath:AT1G76890; -.
DR Araport; AT1G76890; -.
DR TAIR; locus:2036272; AT1G76890.
DR eggNOG; KOG4282; Eukaryota.
DR HOGENOM; CLU_013796_1_1_1; -.
DR InParanoid; Q39117; -.
DR OMA; FESKEPM; -.
DR OrthoDB; 782634at2759; -.
DR PhylomeDB; Q39117; -.
DR PRO; PR:Q39117; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q39117; baseline and differential.
DR Genevisible; Q39117; AT.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR InterPro; IPR044822; Myb_DNA-bind_4.
DR InterPro; IPR001005; SANT/Myb.
DR Pfam; PF13837; Myb_DNA-bind_4; 2.
DR SMART; SM00717; SANT; 2.
DR PROSITE; PS50090; MYB_LIKE; 2.
PE 1: Evidence at protein level;
KW DNA-binding; Nucleus; Reference proteome; Repeat; Transcription;
KW Transcription regulation.
FT CHAIN 1..575
FT /note="Trihelix transcription factor GT-2"
FT /id="PRO_0000401379"
FT DOMAIN 40..98
FT /note="Myb-like 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00133"
FT DOMAIN 390..454
FT /note="Myb-like 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00133"
FT REGION 1..44
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 157..181
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 232..256
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 339..364
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 513..575
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 339..353
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 530..553
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 556..575
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 344
FT /note="Q -> H (in Ref. 2; CAA05997)"
FT /evidence="ECO:0000305"
FT CONFLICT 506
FT /note="Q -> L (in Ref. 2; CAA05997)"
FT /evidence="ECO:0000305"
FT CONFLICT 514
FT /note="Q -> L (in Ref. 2; CAA05997)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 575 AA; 65837 MW; 6DD4C89883F8552B CRC64;
MSGNSEGLLE SSGGGVGGSV EEEKDMKMEE TGEGAGSGGN RWPRPETLAL LRIRSEMDKA
FRDSTLKAPL WEEISRKMME LGYKRSSKKC KEKFENVYKY HKRTKEGRTG KSEGKTYRFF
EELEAFETLS SYQPEPESQP AKSSAVITNA PATSSLIPWI SSSNPSTEKS SSPLKHHHQV
SVQPITTNPT FLAKQPSSTT PFPFYSSNNT TTVSQPPISN DLMNNVSSLN LFSSSTSSST
ASDEEEDHHQ VKSSRKKRKY WKGLFTKLTK ELMEKQEKMQ KRFLETLEYR EKERISREEA
WRVQEIGRIN REHETLIHER SNAAAKDAAI ISFLHKISGG QPQQPQQHNH KPSQRKQYQS
DHSITFESKE PRAVLLDTTI KMGNYDNNHS VSPSSSRWPK TEVEALIRIR KNLEANYQEN
GTKGPLWEEI SAGMRRLGYN RSAKRCKEKW ENINKYFKKV KESNKKRPLD SKTCPYFHQL
EALYNERNKS GAMPLPLPLM VTPQRQLLLS QETQTEFETD QREKVGDKED EEEGESEEDE
YDEEEEGEGD NETSEFEIVL NKTSSPMDIN NNLFT
