TGT3A_ARATH
ID TGT3A_ARATH Reviewed; 323 AA.
AC Q9SDW0;
DT 30-NOV-2010, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 25-MAY-2022, entry version 142.
DE RecName: Full=Trihelix transcription factor GT-3a;
DE AltName: Full=Trihelix DNA-binding protein GT-3a;
GN Name=GT-3A; Synonyms=GT3A; OrderedLocusNames=At5g01380; ORFNames=T10O8.90;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA], FUNCTION, SUBUNIT, SUBCELLULAR
RP LOCATION, TISSUE SPECIFICITY, AND INTERACTION WITH GT-3B.
RC STRAIN=cv. C24, and cv. Columbia;
RX PubMed=15044016; DOI=10.1016/s0014-5793(04)00222-4;
RA Ayadi M., Delaporte V., Li Y.F., Zhou D.X.;
RT "Analysis of GT-3a identifies a distinct subgroup of trihelix DNA-binding
RT transcription factors in Arabidopsis.";
RL FEBS Lett. 562:147-154(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130714; DOI=10.1038/35048507;
RA Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E.,
RA Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M.,
RA Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K.,
RA Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M.,
RA Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L.,
RA O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D.,
RA Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M.,
RA Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L.,
RA Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B.,
RA Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P.,
RA Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M.,
RA Dedhia N., Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D.,
RA Baker J., Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A.,
RA Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I.,
RA Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T.,
RA Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., Langham S.-A.,
RA McCullagh B., Robben J., Grymonprez B., Zimmermann W., Ramsperger U.,
RA Wedler H., Balke K., Wedler E., Peters S., van Staveren M., Dirkse W.,
RA Mooijman P., Klein Lankhorst R., Weitzenegger T., Bothe G., Rose M.,
RA Hauf J., Berneiser S., Hempel S., Feldpausch M., Lamberth S.,
RA Villarroel R., Gielen J., Ardiles W., Bents O., Lemcke K., Kolesov G.,
RA Mayer K.F.X., Rudd S., Schoof H., Schueller C., Zaccaria P., Mewes H.-W.,
RA Bevan M., Fransz P.F.;
RT "Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana.";
RL Nature 408:823-826(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Quinitio C., Chen H., Kim C.J., Shinn P., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Probable transcription factor that binds specifically to the
CC core DNA sequence 5'-GTTAC-3'. {ECO:0000269|PubMed:15044016}.
CC -!- SUBUNIT: Homodimer. Heterodimer with GT-3B.
CC {ECO:0000269|PubMed:15044016}.
CC -!- INTERACTION:
CC Q9SDW0; Q9SFD5: ADA2A; NbExp=4; IntAct=EBI-9348720, EBI-979206;
CC Q9SDW0; Q7X9H6: AGL79; NbExp=4; IntAct=EBI-9348720, EBI-1238497;
CC Q9SDW0; Q6X7J9: WOX4; NbExp=3; IntAct=EBI-9348720, EBI-4459694;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:15044016}.
CC -!- TISSUE SPECIFICITY: Predominantly expressed in roots and flower buds.
CC {ECO:0000269|PubMed:15044016}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AF206715; AAF17610.1; -; Genomic_DNA.
DR EMBL; AY271677; AAP13347.1; -; mRNA.
DR EMBL; AL161746; CAB81921.1; -; Genomic_DNA.
DR EMBL; CP002688; AED90334.1; -; Genomic_DNA.
DR EMBL; BT028926; ABI49473.1; -; mRNA.
DR PIR; T48160; T48160.
DR RefSeq; NP_195758.1; NM_120216.4.
DR AlphaFoldDB; Q9SDW0; -.
DR SMR; Q9SDW0; -.
DR BioGRID; 17171; 25.
DR IntAct; Q9SDW0; 24.
DR STRING; 3702.AT5G01380.1; -.
DR iPTMnet; Q9SDW0; -.
DR PaxDb; Q9SDW0; -.
DR PRIDE; Q9SDW0; -.
DR ProteomicsDB; 234408; -.
DR EnsemblPlants; AT5G01380.1; AT5G01380.1; AT5G01380.
DR GeneID; 831895; -.
DR Gramene; AT5G01380.1; AT5G01380.1; AT5G01380.
DR KEGG; ath:AT5G01380; -.
DR Araport; AT5G01380; -.
DR TAIR; locus:2179192; AT5G01380.
DR eggNOG; KOG4282; Eukaryota.
DR HOGENOM; CLU_063336_1_0_1; -.
DR InParanoid; Q9SDW0; -.
DR OMA; WSEATEP; -.
DR OrthoDB; 1337104at2759; -.
DR PhylomeDB; Q9SDW0; -.
DR PRO; PR:Q9SDW0; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9SDW0; baseline and differential.
DR Genevisible; Q9SDW0; AT.
DR GO; GO:0005634; C:nucleus; IDA:UniProtKB.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0042802; F:identical protein binding; IPI:UniProtKB.
DR GO; GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IPI:TAIR.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:TAIR.
DR InterPro; IPR044822; Myb_DNA-bind_4.
DR InterPro; IPR001005; SANT/Myb.
DR InterPro; IPR027759; Trihelix_TF_GT3.
DR PANTHER; PTHR21654:SF79; PTHR21654:SF79; 1.
DR Pfam; PF13837; Myb_DNA-bind_4; 1.
DR SMART; SM00717; SANT; 1.
DR PROSITE; PS50090; MYB_LIKE; 1.
PE 1: Evidence at protein level;
KW DNA-binding; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..323
FT /note="Trihelix transcription factor GT-3a"
FT /id="PRO_0000401380"
FT DOMAIN 52..108
FT /note="Myb-like"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00133"
FT REGION 1..51
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 147..176
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 190..220
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 269..297
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..19
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 190..204
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 323 AA; 38273 MW; 7A359042B5B6E10C CRC64;
MDRRNPFQHH HHHHQLHHHL IQQQQLPPPP LSTTATMDPG GGGGGGERIP QWSIEETKEL
LAIREELDQT FMETKRNKLL WEVVAAKMAD KGFVRSAEQC KSKWKNLVTR YKACETTEPD
AIRQQFPFYN EIQSIFEARM QRMLWSEATE PSTSSKRKHH QFSSDDEEEE VDEPNQDINE
ELLSLVETQK RETEVITTST STNPRKRAKK GKGVASGTKA ETAGNTLKDI LEEFMRQTVK
MEKEWRDAWE MKEIEREKRE KEWRRRMAEL EEERAATERR WMEREEERRL REEARAQKRD
SLIDALLNRL NRDHNDDHHN QGF
