TGT3B_ARATH
ID TGT3B_ARATH Reviewed; 289 AA.
AC O80450; Q84QS1;
DT 30-NOV-2010, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1998, sequence version 1.
DT 25-MAY-2022, entry version 150.
DE RecName: Full=Trihelix transcription factor GT-3b;
DE AltName: Full=Transcription factor GT-1-like;
DE AltName: Full=Trihelix DNA-binding protein GT-3b;
GN Name=GT-3B; Synonyms=GT1L, GT3B; OrderedLocusNames=At2g38250;
GN ORFNames=F16M14.18;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], AND INTERACTION WITH GT-3A.
RC STRAIN=cv. Columbia;
RX PubMed=15044016; DOI=10.1016/s0014-5793(04)00222-4;
RA Ayadi M., Delaporte V., Li Y.F., Zhou D.X.;
RT "Analysis of GT-3a identifies a distinct subgroup of trihelix DNA-binding
RT transcription factors in Arabidopsis.";
RL FEBS Lett. 562:147-154(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, AND INDUCTION.
RX PubMed=15310827; DOI=10.1104/pp.104.041442;
RA Park H.C., Kim M.L., Kang Y.H., Jeon J.M., Yoo J.H., Kim M.C., Park C.Y.,
RA Jeong J.C., Moon B.C., Lee J.H., Yoon H.W., Lee S.H., Chung W.S., Lim C.O.,
RA Lee S.Y., Hong J.C., Cho M.J.;
RT "Pathogen- and NaCl-induced expression of the SCaM-4 promoter is mediated
RT in part by a GT-1 box that interacts with a GT-1-like transcription
RT factor.";
RL Plant Physiol. 135:2150-2161(2004).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [5]
RP IDENTIFICATION BY MASS SPECTROMETRY, AND SUBUNIT.
RX PubMed=17560376; DOI=10.1016/j.molcel.2007.05.007;
RA Baeckstroem S., Elfving N., Nilsson R., Wingsle G., Bjoerklund S.;
RT "Purification of a plant mediator from Arabidopsis thaliana identifies PFT1
RT as the Med25 subunit.";
RL Mol. Cell 26:717-729(2007).
CC -!- FUNCTION: Probable transcription factor that may play a role in the
CC induction of CAM4 in response to pathogen and salt.
CC {ECO:0000269|PubMed:15310827}.
CC -!- SUBUNIT: Heterodimer with GT-3A. Associated with the mediator complex.
CC {ECO:0000269|PubMed:17560376}.
CC -!- INTERACTION:
CC O80450; Q9LR91: At1g24040/T23E23_24; NbExp=3; IntAct=EBI-1571089, EBI-15194797;
CC O80450; F4JI72: At4g03250; NbExp=3; IntAct=EBI-1571089, EBI-15192535;
CC O80450; Q9ZT48: ATE1; NbExp=3; IntAct=EBI-1571089, EBI-25522944;
CC O80450; Q9SFV2: FHA2; NbExp=3; IntAct=EBI-1571089, EBI-15191747;
CC O80450; O80961: MLO12; NbExp=3; IntAct=EBI-1571089, EBI-17061436;
CC O80450; Q9LSI7: MYB35; NbExp=3; IntAct=EBI-1571089, EBI-25523050;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- INDUCTION: By salt and infection with the bacterial pathogen P.syringae
CC pv tomato. {ECO:0000269|PubMed:15310827}.
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DR EMBL; AY271678; AAP13348.1; -; mRNA.
DR EMBL; AF453582; AAL50816.1; -; mRNA.
DR EMBL; AC003028; AAC27174.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC09513.1; -; Genomic_DNA.
DR PIR; T01257; T01257.
DR RefSeq; NP_181360.1; NM_129382.3.
DR AlphaFoldDB; O80450; -.
DR SMR; O80450; -.
DR BioGRID; 3746; 28.
DR IntAct; O80450; 24.
DR STRING; 3702.AT2G38250.1; -.
DR iPTMnet; O80450; -.
DR PaxDb; O80450; -.
DR PRIDE; O80450; -.
DR ProteomicsDB; 246413; -.
DR EnsemblPlants; AT2G38250.1; AT2G38250.1; AT2G38250.
DR GeneID; 818404; -.
DR Gramene; AT2G38250.1; AT2G38250.1; AT2G38250.
DR KEGG; ath:AT2G38250; -.
DR Araport; AT2G38250; -.
DR TAIR; locus:2042847; AT2G38250.
DR eggNOG; KOG4282; Eukaryota.
DR HOGENOM; CLU_063336_1_0_1; -.
DR InParanoid; O80450; -.
DR OMA; NERILME; -.
DR OrthoDB; 1337104at2759; -.
DR PRO; PR:O80450; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; O80450; baseline and differential.
DR Genevisible; O80450; AT.
DR GO; GO:0016592; C:mediator complex; IDA:UniProtKB.
DR GO; GO:0005730; C:nucleolus; HDA:TAIR.
DR GO; GO:0005634; C:nucleus; IDA:TAIR.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:TAIR.
DR InterPro; IPR044822; Myb_DNA-bind_4.
DR InterPro; IPR001005; SANT/Myb.
DR InterPro; IPR027759; Trihelix_TF_GT3.
DR PANTHER; PTHR21654:SF87; PTHR21654:SF87; 1.
DR Pfam; PF13837; Myb_DNA-bind_4; 1.
DR SMART; SM00717; SANT; 1.
DR PROSITE; PS50090; MYB_LIKE; 1.
PE 1: Evidence at protein level;
KW Coiled coil; DNA-binding; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..289
FT /note="Trihelix transcription factor GT-3b"
FT /id="PRO_0000401381"
FT DOMAIN 42..98
FT /note="Myb-like"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00133"
FT REGION 137..200
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 223..275
FT /evidence="ECO:0000255"
FT MOTIF 65..81
FT /note="Bipartite nuclear localization signal"
FT /evidence="ECO:0000255"
FT MOTIF 179..188
FT /note="Nuclear localization signal"
FT /evidence="ECO:0000255"
FT CONFLICT 7
FT /note="H -> P (in Ref. 1; AAP13348)"
FT /evidence="ECO:0000305"
FT CONFLICT 163
FT /note="V -> A (in Ref. 1; AAP13348)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 289 AA; 34307 MW; CEE46E6022724754 CRC64;
MDGHQHHHLH QLQYLNKHHL HTQSQTPEIA SPVAVGDRFP QWSVEETKEL IGIRGELDQT
FMETKRNKLL WEVISNKMRD KSFPRSPEQC KCKWKNLVTR FKGCETMEAE TARQQFPFYD
DMQNIFTTRM QRMLWAESEG GGGGTSGAAR KREYSSDEEE ENVNEELVDV SNDPKILNPK
KNIAKKRKGG SNSSNSNNGV REVLEEFMRH QVRMESEWRE GWEAREKERA EKEEEWRRKM
EELEKERLAM ERMWRDREEQ RRSREEMRAE KRDSLINALL AKLTRDGSL
