ID   THADA_CHLAE             Reviewed;        1953 AA.
AC   A8C752;
DT   22-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   13-NOV-2007, sequence version 1.
DT   25-MAY-2022, entry version 32.
DE   RecName: Full=Thyroid adenoma-associated protein homolog;
GN   Name=THADA;
OS   Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Chlorocebus.
OX   NCBI_TaxID=9534;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=17889454; DOI=10.1016/j.gene.2007.06.029;
RA   Drieschner N., Kerschling S., Soller J.T., Rippe V., Belge G.,
RA   Bullerdiek J., Nimzyk R.;
RT   "A domain of the thyroid adenoma associated gene (THADA) conserved in
RT   vertebrates becomes destroyed by chromosomal rearrangements observed in
RT   thyroid adenomas.";
RL   Gene 403:110-117(2007).
CC   -!- SIMILARITY: Belongs to the THADA family. {ECO:0000305}.
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DR   EMBL; EF222205; ABQ10599.1; -; mRNA.
DR   AlphaFoldDB; A8C752; -.
DR   SMR; A8C752; -.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR019442; THADA/TRM732_DUF2428.
DR   Pfam; PF10350; DUF2428; 1.
DR   SUPFAM; SSF48371; SSF48371; 2.
PE   2: Evidence at transcript level;
KW   Coiled coil; Phosphoprotein.
FT   CHAIN           1..1953
FT                   /note="Thyroid adenoma-associated protein homolog"
FT                   /id="PRO_0000344056"
FT   COILED          888..918
FT                   /evidence="ECO:0000255"
FT   MOD_RES         1015
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q6YHU6"
FT   MOD_RES         1024
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q6YHU6"
FT   MOD_RES         1161
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q6YHU6"
SQ   SEQUENCE   1953 AA;  219545 MW;  5E4B8B297192EDC0 CRC64;
     MGVKKKKEMQ VAVLTICHQD LETLKSFADA EGKNLASLLL RCVQLTDGVS QIHYVKQIVP
     LLEKVGKNGV CDPTIQSCLD ILAGIYLSLS LKNPLKKVLA SSLNSLPDFF LPEAVHRFTS
     RLQEELNTTD LYSYRKVIDN ISSCMENFNL GRAGVNNLLK NVLHFLQKSL IEIVEENRKC
     AGNHIIQTQL MNDLLVGIRV SMTLVQKVQD FQGNLWKASN SPIWQNMCGL LSIFTKFLSD
     DDLLQTVQST SGLAITLFIK TMFHPSEKIP HLISSVLLRS VDCTSVPEWF MNSCRSLCCG
     NVSGSAVLFL CQGTLAMLDW QNGSMGRSGE ALLLDTAHVL FTLSSQIKEP TLEMFLSRIM
     ASWTNSAIQV LESSSPSLRD SLNGNSSIVG RLLEYVYTHW EHPLDALRHQ TKIMFKNLLQ
     MHRLTVEGAV LVPDPFFVKL TESLLRLEWH IKGKYMCLGC LVECIGIEHI LAIDKTIPSQ
     ILEVMGDQSL VPYASDLLET MFKNHKSHLK SQTAESSWID QWHETWVSPL LFILCEGNLD
     QKSYVIDYYL PKLLSYSPES LQYMVKILQT SIDAKTGQEQ SFPSLGSCNS RGALGALMAC
     LRIARAHGHL QSATDTWENL VSGARIKQGL IHQHCQVRID TLGLLCESNR STEIVSMEEM
     QWIQFFITYN LNSQSPGVRQ QICSLLKKLF CRIQESSQVL YKLEQNKSKH EPEKELTKQH
     PSVSLQQYKN FMSSICNSLF EALFPGSSYS TRFSALTILG SIAEVFHVPE GRIYTVYQLN
     HDIDVGRFQA LMECFTSTFE DVKMLAFDLL MKLSKTAVHF QDSEKLQGLF QAALALSTST
     KPYDCVTASY LLNFLIWQDA LPSSLSVYLT QQVARGDGDR PASVVERNTL MVIKCLMENL
     EEEVYQAENS LLQAAASFPM YGRVHCITGA LQKLSLNSLQ LVSEWRPVVE KLLLMSYRLS
     TVVSPVIQSS SPEGLIPMDT DSESASRLQM ILNEIQPRDT NDYFNQAKIL KEHDSFDMKD
     LNASVVNIDI STEIKGKEVK TCDVTAQMVL VCCWRSMKEV ALLLGTLCQL LPMQPVPESS
     DGLLTVEQVK EIGDYFKQHL LQSRHRGAFE LAYTGFVKLT EVLNRCPNVS LQKLPEQWLW
     SVLEEIKCSD PSSKLCATRR SAGIPFYIQA LLASEPKKGK MDLLKITMKE LISLAGPTDD
     LQSTVPQVHA LNILRALFRD TRLGENIIPY VADGAKAAIL GFTSPVWAVR NSSTLLFSAL
     ITRIFGVKRA KDELSKTNRM TGREFFSRFP ELYPFLLKQL ETVANAVDSD MGEPNRHPSM
     FLLLLVLERL YPSPMDGTSS ALSMGPFVPF IMRCGHSPVY HSREMAARAL VPFVMIDHIP
     NTIRTLLATL PSCTDQCFRQ NRIHGTLLQV FHLLQAYSDS KHRTNSDFQH ELTDITVCTK
     AKLWLAKRQN PCLVTRAVYI DILFLLTCCL NKSVKDNQPV LESLGLWEEV RGIISGSELI
     TGFPCAFKAP GLPQYLESLT RLTIAAVWAA AAKSGERERD VPISFSQLLE SAFPEVRSLT
     LEALLEKFLS AASGLGENGL PPLLCNMEEK FLLLAMKENH PECFCKILKI LHCMDPGEWL
     PQTEHCVHLT PKEFLIWTMD VASNERSEIQ SVALRLASKV ISHHMQTCVE NRELIAAELK
     QWVQLVILSC EDHLPTESRL AVVEVLTSTA PLFLTNPHPI LELQDTLALW KCVLTLLQSE
     EQAVRDAATE TVTTAMSQEN TCQSTEFAFC QVDASIALAL ALAVLCDLLQ QWNQLASGLP
     ILLRWLLGDS DDLVVCVESL HQVEEDYLFE KAEVNFWAET LIFVKYLCKH LFCLLSKSGW
     RLPSPEMLCH LQRMVSEQCR LLSQLFRELP PAAEFVKTVE FTRLRIQEER TLACLKLLAF
     LEGKEGEDTL VLSVWDSSAE ARQLTLPRTE AAC