ID   BRIX_PYRFU              Reviewed;         223 AA.
AC   Q8TZI2;
DT   29-AUG-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2002, sequence version 1.
DT   25-MAY-2022, entry version 86.
DE   RecName: Full=Probable Brix domain-containing ribosomal biogenesis protein {ECO:0000255|HAMAP-Rule:MF_00699};
GN   OrderedLocusNames=PF2010;
OS   Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1).
OC   Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC   Pyrococcus.
OX   NCBI_TaxID=186497;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43587 / DSM 3638 / JCM 8422 / Vc1;
RX   PubMed=10430560; DOI=10.1093/genetics/152.4.1299;
RA   Maeder D.L., Weiss R.B., Dunn D.M., Cherry J.L., Gonzalez J.M.,
RA   DiRuggiero J., Robb F.T.;
RT   "Divergence of the hyperthermophilic archaea Pyrococcus furiosus and P.
RT   horikoshii inferred from complete genomic sequences.";
RL   Genetics 152:1299-1305(1999).
CC   -!- FUNCTION: Probably involved in the biogenesis of the ribosome.
CC       {ECO:0000255|HAMAP-Rule:MF_00699}.
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DR   EMBL; AE009950; AAL82134.1; -; Genomic_DNA.
DR   RefSeq; WP_011013155.1; NZ_CP023154.1.
DR   AlphaFoldDB; Q8TZI2; -.
DR   SMR; Q8TZI2; -.
DR   STRING; 186497.PF2010; -.
DR   EnsemblBacteria; AAL82134; AAL82134; PF2010.
DR   GeneID; 41713836; -.
DR   KEGG; pfu:PF2010; -.
DR   PATRIC; fig|186497.12.peg.2087; -.
DR   eggNOG; arCOG03247; Archaea.
DR   HOGENOM; CLU_107897_0_0_2; -.
DR   OMA; VKIWIME; -.
DR   OrthoDB; 61656at2157; -.
DR   PhylomeDB; Q8TZI2; -.
DR   Proteomes; UP000001013; Chromosome.
DR   GO; GO:0019843; F:rRNA binding; IEA:InterPro.
DR   GO; GO:0006364; P:rRNA processing; IEA:InterPro.
DR   HAMAP; MF_00699; BriX; 1.
DR   InterPro; IPR007109; Brix.
DR   InterPro; IPR023548; Brix_dom_Rbsml_bgen_prot.
DR   SMART; SM00879; Brix; 1.
DR   PROSITE; PS50833; BRIX; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Ribosome biogenesis.
FT   CHAIN           1..223
FT                   /note="Probable Brix domain-containing ribosomal biogenesis
FT                   protein"
FT                   /id="PRO_0000120277"
FT   DOMAIN          1..196
FT                   /note="Brix"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00699"
SQ   SEQUENCE   223 AA;  26070 MW;  CCC88009D47A2F6B CRC64;
     MMLITTSHRP TRRTRSFGHD LERVFPNSLY LTRGKKTIQE LLMEAYDRGY ERLLILNVWK
     GNPLKMTFIK VHPEDWGYLG YLYLHGIKLQ REMGFKGLNP IREDMPLVVT TAKRVGWDHI
     AFAQVFAELT TGKFVPRGDK SLTYIADKYD TDVIAVIERH PRGMVINFYR LDVTKDRPVG
     PLINVKIWIM EDGRRWDYKE ALGIKVPRRE KGEGQESSSE NRD