ID   BRIX_PYRHO              Reviewed;         224 AA.
AC   O74104; O59520;
DT   29-AUG-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1998, sequence version 1.
DT   25-MAY-2022, entry version 103.
DE   RecName: Full=Probable Brix domain-containing ribosomal biogenesis protein {ECO:0000255|HAMAP-Rule:MF_00699};
GN   OrderedLocusNames=PH1900;
OS   Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC
OS   100139 / OT-3).
OC   Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC   Pyrococcus.
OX   NCBI_TaxID=70601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3;
RX   PubMed=9679194; DOI=10.1093/dnares/5.2.55;
RA   Kawarabayasi Y., Sawada M., Horikawa H., Haikawa Y., Hino Y., Yamamoto S.,
RA   Sekine M., Baba S., Kosugi H., Hosoyama A., Nagai Y., Sakai M., Ogura K.,
RA   Otsuka R., Nakazawa H., Takamiya M., Ohfuku Y., Funahashi T., Tanaka T.,
RA   Kudoh Y., Yamazaki J., Kushida N., Oguchi A., Aoki K., Yoshizawa T.,
RA   Nakamura Y., Robb F.T., Horikoshi K., Masuchi Y., Shizuya H., Kikuchi H.;
RT   "Complete sequence and gene organization of the genome of a hyper-
RT   thermophilic archaebacterium, Pyrococcus horikoshii OT3.";
RL   DNA Res. 5:55-76(1998).
CC   -!- FUNCTION: Probably involved in the biogenesis of the ribosome.
CC       {ECO:0000255|HAMAP-Rule:MF_00699}.
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DR   EMBL; BA000001; BAA31023.1; -; Genomic_DNA.
DR   PIR; H71203; H71203.
DR   RefSeq; WP_010885963.1; NC_000961.1.
DR   AlphaFoldDB; O74104; -.
DR   SMR; O74104; -.
DR   STRING; 70601.3258340; -.
DR   EnsemblBacteria; BAA31023; BAA31023; BAA31023.
DR   GeneID; 1442745; -.
DR   KEGG; pho:PH1900; -.
DR   eggNOG; arCOG03247; Archaea.
DR   OMA; VKIWIME; -.
DR   OrthoDB; 61656at2157; -.
DR   Proteomes; UP000000752; Chromosome.
DR   GO; GO:0019843; F:rRNA binding; IEA:InterPro.
DR   GO; GO:0006364; P:rRNA processing; IEA:InterPro.
DR   HAMAP; MF_00699; BriX; 1.
DR   InterPro; IPR007109; Brix.
DR   InterPro; IPR023548; Brix_dom_Rbsml_bgen_prot.
DR   SMART; SM00879; Brix; 1.
DR   PROSITE; PS50833; BRIX; 1.
PE   3: Inferred from homology;
KW   Ribosome biogenesis.
FT   CHAIN           1..224
FT                   /note="Probable Brix domain-containing ribosomal biogenesis
FT                   protein"
FT                   /id="PRO_0000120278"
FT   DOMAIN          1..196
FT                   /note="Brix"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00699"
SQ   SEQUENCE   224 AA;  26126 MW;  23483F069B0A8F08 CRC64;
     MMLITTSHRP TRRTRSFGHD LERVIPNSLY LTRGKKTIQE LLMEAYDRGY ERLLIINVWK
     GNPLKMTFIK VHPEDWGYLG YLYLHGVKLQ REMGFKGLNP IREDMPLVIT TAKRVGLDHL
     AFAQVFSELT TGKFVPRGDK SLLSIADRYN TDVLAVIERH PRGIVINFYR LDITKDRPVG
     PLINVKIWIM EDGRRWDYKE AFGIKVPPRR REFEGKRGEG KNSD