ID   THAP1_THAPI             Reviewed;         126 AA.
AC   E0X9F6; Q7M4K8;
DT   16-JAN-2019, integrated into UniProtKB/Swiss-Prot.
DT   02-NOV-2010, sequence version 1.
DT   25-MAY-2022, entry version 25.
DE   RecName: Full=Allergen Tha p 1 {ECO:0000303|PubMed:12580804};
DE   AltName: Allergen=Tha p 1 {ECO:0000303|PubMed:12580804};
DE   Flags: Precursor;
OS   Thaumetopoea pityocampa (Pine processionary moth) (Bombyx pityocampa).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Noctuoidea;
OC   Notodontidae; Thaumetopoeinae; Thaumetopoea.
OX   NCBI_TaxID=208016 {ECO:0000312|EMBL:ADK47876.1};
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RA   Rodriguez-Mahillo A.I., Gonzalez-Munoz M., Vega J., Battisti A., Roques A.,
RA   Moneo I.;
RL   Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   PROTEIN SEQUENCE OF 19-36, ALLERGEN, AND DEVELOPMENTAL STAGE.
RC   TISSUE=Larva {ECO:0000303|PubMed:12580804};
RX   PubMed=12580804; DOI=10.1034/j.1398-9995.2003.23724.x;
RA   Moneo I., Vega J.M., Caballero M.L., Vega J., Alday E.;
RT   "Isolation and characterization of Tha p 1, a major allergen from the pine
RT   processionary caterpillar Thaumetopoea pityocampa.";
RL   Allergy 58:34-37(2003).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC   -!- DEVELOPMENTAL STAGE: Larvae. {ECO:0000269|PubMed:12580804}.
CC   -!- ALLERGEN: Causes an allergic reaction in human. Binds to IgE.
CC       {ECO:0000269|PubMed:12580804}.
CC   -!- SIMILARITY: Belongs to the insect A10/OS-D protein family.
CC       {ECO:0000305}.
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DR   EMBL; GQ888732; ADK47876.1; -; mRNA.
DR   EMBL; HE962022; CCJ09295.1; -; mRNA.
DR   PIR; A59396; A59396.
DR   AlphaFoldDB; E0X9F6; -.
DR   SMR; E0X9F6; -.
DR   Allergome; 3496; Tha p 1.0101.
DR   Allergome; 917; Tha p 1.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   Gene3D; 1.10.2080.10; -; 1.
DR   InterPro; IPR005055; A10/PebIII.
DR   InterPro; IPR036682; OS_D_A10/PebIII_sf.
DR   PANTHER; PTHR11257; PTHR11257; 1.
DR   Pfam; PF03392; OS-D; 1.
DR   SUPFAM; SSF100910; SSF100910; 1.
PE   1: Evidence at protein level;
KW   Allergen; Direct protein sequencing; Secreted; Signal.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000269|PubMed:12580804"
FT   CHAIN           19..126
FT                   /note="Allergen Tha p 1"
FT                   /evidence="ECO:0000305|PubMed:12580804"
FT                   /id="PRO_5010961907"
SQ   SEQUENCE   126 AA;  14540 MW;  5232A9E4AF91FA11 CRC64;
     MKLLILALTC AAAVWARPGE TYSDKYDTID VNEVLQSERL LKGYVECLLD KGRCTPDGKE
     LKDTLPDALE HECSKCTEKQ KSGADTVIRH LVNKRPELWK ELAVKYDPEN IYQERYKDRL
     ESVKEH