BRK1A_XENLA
ID BRK1A_XENLA Reviewed; 75 AA.
AC Q6P7G6;
DT 03-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 48.
DE RecName: Full=Probable protein BRICK1-A;
GN Name=brk1-a;
OS Xenopus laevis (African clawed frog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX NCBI_TaxID=8355;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Lung;
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (NOV-2003) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Involved in regulation of actin and microtubule organization.
CC Part of a WAVE complex that activates the Arp2/3 complex (By
CC similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the BRK1 family. {ECO:0000305}.
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DR EMBL; BC061677; AAH61677.1; -; mRNA.
DR RefSeq; NP_001165164.1; NM_001171693.1.
DR AlphaFoldDB; Q6P7G6; -.
DR SMR; Q6P7G6; -.
DR DNASU; 399042; -.
DR GeneID; 399042; -.
DR KEGG; xla:399042; -.
DR CTD; 399042; -.
DR Xenbase; XB-GENE-6254645; brk1.L.
DR OrthoDB; 1579787at2759; -.
DR Proteomes; UP000186698; Chromosome 4L.
DR Bgee; 399042; Expressed in lung and 19 other tissues.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR GO; GO:0031209; C:SCAR complex; IEA:InterPro.
DR GO; GO:0044877; F:protein-containing complex binding; IEA:InterPro.
DR GO; GO:0007015; P:actin filament organization; IEA:InterPro.
DR InterPro; IPR033378; BRICK1.
DR PANTHER; PTHR33668; PTHR33668; 1.
PE 3: Inferred from homology;
KW Coiled coil; Cytoplasm; Cytoskeleton; Reference proteome.
FT CHAIN 1..75
FT /note="Probable protein BRICK1-A"
FT /id="PRO_0000283650"
FT COILED 41..72
FT /evidence="ECO:0000255"
SQ SEQUENCE 75 AA; 8747 MW; 872F5422FCF0C5E6 CRC64;
MASQDDPVQR EIHQDWANRE YIEVITSSIK KIADFLNSFD MSCRSRLATL NEKLTALERR
IEYIEARVTK GETLT