ID   THEM6_RAT               Reviewed;         207 AA.
AC   Q5XIE1;
DT   01-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   03-AUG-2022, entry version 88.
DE   RecName: Full=Protein THEM6;
DE   Flags: Precursor;
GN   Name=Them6;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Heart;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the THEM6 family. {ECO:0000305}.
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DR   EMBL; BC083742; AAH83742.1; -; mRNA.
DR   RefSeq; NP_001007659.1; NM_001007658.1.
DR   AlphaFoldDB; Q5XIE1; -.
DR   SMR; Q5XIE1; -.
DR   STRING; 10116.ENSRNOP00000007773; -.
DR   GlyGen; Q5XIE1; 1 site.
DR   jPOST; Q5XIE1; -.
DR   PaxDb; Q5XIE1; -.
DR   PRIDE; Q5XIE1; -.
DR   Ensembl; ENSRNOT00000007773; ENSRNOP00000007773; ENSRNOG00000005929.
DR   GeneID; 300015; -.
DR   KEGG; rno:300015; -.
DR   UCSC; RGD:1359378; rat.
DR   CTD; 51337; -.
DR   RGD; 1359378; Them6.
DR   eggNOG; KOG4366; Eukaryota.
DR   GeneTree; ENSGT00390000004859; -.
DR   HOGENOM; CLU_091107_0_1_1; -.
DR   InParanoid; Q5XIE1; -.
DR   OMA; RDIDMCH; -.
DR   OrthoDB; 1195870at2759; -.
DR   PhylomeDB; Q5XIE1; -.
DR   TreeFam; TF324625; -.
DR   PRO; PR:Q5XIE1; -.
DR   Proteomes; UP000002494; Chromosome 7.
DR   Bgee; ENSRNOG00000005929; Expressed in testis and 19 other tissues.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   InterPro; IPR029069; HotDog_dom_sf.
DR   SUPFAM; SSF54637; SSF54637; 1.
PE   2: Evidence at transcript level;
KW   Glycoprotein; Phosphoprotein; Reference proteome; Secreted; Signal.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000255"
FT   CHAIN           22..207
FT                   /note="Protein THEM6"
FT                   /id="PRO_0000285638"
FT   MOD_RES         199
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q8WUY1"
FT   CARBOHYD        188
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   207 AA;  23748 MW;  9F47F40C67CC62F6 CRC64;
     MMELLVVSLS LALAFFALLD GWYLVRVPCA VLRARLLQPR VRDLLAEQLY AGRVLPSDLD
     LLLHMNNARY LREADVARAA HLTRCGVLGA LRDLGAHTVL AASCARYRRS LRLFEPFEVH
     TRLLGWDDRA FYLEARFVSL RDGFVCALLR FRQHVLGTSP DRVVQHLCKR RVEPPELPED
     LKHWITYNET SSQLLRAESG LSDRKDQ