ID   BRK1B_XENLA             Reviewed;          75 AA.
AC   A2BD66;
DT   03-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT   20-FEB-2007, sequence version 1.
DT   03-AUG-2022, entry version 41.
DE   RecName: Full=Probable protein BRICK1-B;
GN   Name=brk1-b;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Hind limb;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in regulation of actin and microtubule organization.
CC       Part of a WAVE complex that activates the Arp2/3 complex (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the BRK1 family. {ECO:0000305}.
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DR   EMBL; BC128952; AAI28953.1; -; mRNA.
DR   RefSeq; NP_001165171.1; NM_001171700.1.
DR   AlphaFoldDB; A2BD66; -.
DR   SMR; A2BD66; -.
DR   DNASU; 100037105; -.
DR   GeneID; 100037105; -.
DR   KEGG; xla:100037105; -.
DR   CTD; 100037105; -.
DR   Xenbase; XB-GENE-1009803; brk1.S.
DR   OMA; MPCCCWE; -.
DR   OrthoDB; 1579787at2759; -.
DR   Proteomes; UP000186698; Chromosome 4S.
DR   Bgee; 100037105; Expressed in internal ear and 19 other tissues.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR   GO; GO:0031209; C:SCAR complex; IEA:InterPro.
DR   GO; GO:0044877; F:protein-containing complex binding; IEA:InterPro.
DR   GO; GO:0007015; P:actin filament organization; IEA:InterPro.
DR   InterPro; IPR033378; BRICK1.
DR   PANTHER; PTHR33668; PTHR33668; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Cytoplasm; Cytoskeleton; Reference proteome.
FT   CHAIN           1..75
FT                   /note="Probable protein BRICK1-B"
FT                   /id="PRO_0000283649"
FT   COILED          41..72
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   75 AA;  8791 MW;  722E107CFD40C457 CRC64;
     MASQEDPVQR EIHQDWANRE YIEVITSSIK KIADFLNSFD MSCRSRLATL NEKLTTLERR
     IEYIEARVTK GETLT