ID   BRK1_MAIZE              Reviewed;          84 AA.
AC   Q8RW98;
DT   06-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2002, sequence version 1.
DT   25-MAY-2022, entry version 85.
DE   RecName: Full=Protein BRICK1;
GN   Name=BRK1;
OS   Zea mays (Maize).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC   Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea.
OX   NCBI_TaxID=4577;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], AND TISSUE SPECIFICITY.
RC   STRAIN=cv. Wisconsin 64A;
RX   PubMed=12015123; DOI=10.1016/s0960-9822(02)00819-9;
RA   Frank M.J., Smith L.G.;
RT   "A small, novel protein highly conserved in plants and animals promotes the
RT   polarized growth and division of maize leaf epidermal cells.";
RL   Curr. Biol. 12:849-853(2002).
CC   -!- FUNCTION: Promotes multiple, actin-dependent cell polarization events
CC       in the developing leaf epidermis. Involved in regulation of actin and
CC       microtubule organization. Part of a WAVE complex that activates the
CC       Arp2/3 complex.
CC   -!- SUBUNIT: Binds SCAR. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton.
CC   -!- TISSUE SPECIFICITY: Expressed in expanding leaves, embryos, ear
CC       primordia, and roots. Very low expression in mature leaf tissue.
CC       {ECO:0000269|PubMed:12015123}.
CC   -!- SIMILARITY: Belongs to the BRK1 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AY093614; AAM18794.1; -; mRNA.
DR   RefSeq; NP_001105190.1; NM_001111720.2.
DR   AlphaFoldDB; Q8RW98; -.
DR   SMR; Q8RW98; -.
DR   STRING; 4577.GRMZM5G842058_P01; -.
DR   PaxDb; Q8RW98; -.
DR   EnsemblPlants; Zm00001eb259430_T001; Zm00001eb259430_P001; Zm00001eb259430.
DR   GeneID; 542086; -.
DR   Gramene; Zm00001eb259430_T001; Zm00001eb259430_P001; Zm00001eb259430.
DR   KEGG; zma:542086; -.
DR   MaizeGDB; 854976; -.
DR   eggNOG; ENOG502S3PY; Eukaryota.
DR   HOGENOM; CLU_175202_0_0_1; -.
DR   OrthoDB; 1579787at2759; -.
DR   Proteomes; UP000007305; Chromosome 5.
DR   ExpressionAtlas; Q8RW98; baseline and differential.
DR   Genevisible; Q8RW98; ZM.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR   GO; GO:0031209; C:SCAR complex; IBA:GO_Central.
DR   GO; GO:0042802; F:identical protein binding; IDA:UniProtKB.
DR   GO; GO:0044877; F:protein-containing complex binding; IEA:InterPro.
DR   GO; GO:0007015; P:actin filament organization; IEA:InterPro.
DR   GO; GO:0048870; P:cell motility; IBA:GO_Central.
DR   GO; GO:0008064; P:regulation of actin polymerization or depolymerization; IBA:GO_Central.
DR   InterPro; IPR033378; BRICK1.
DR   PANTHER; PTHR33668; PTHR33668; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; Cytoplasm; Cytoskeleton; Reference proteome.
FT   CHAIN           1..84
FT                   /note="Protein BRICK1"
FT                   /id="PRO_0000165369"
FT   COILED          45..79
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   84 AA;  9324 MW;  61F7DED4F4B77E01 CRC64;
     MGRGGGMGNP VNVGIAVQAD WENREFISNI SLNVRRLFDF LLRFEATTKS KLASLNEKLD
     ILERKLEVLE VQVGSATTNP SVFN