ID   BRK3_PELNI              Reviewed;          14 AA.
AC   Q7LZ53;
DT   10-MAY-2004, integrated into UniProtKB/Swiss-Prot.
DT   15-DEC-2003, sequence version 1.
DT   26-FEB-2020, entry version 40.
DE   RecName: Full=Bradykinin-like peptide 3;
OS   Pelophylax nigromaculatus (Black-spotted frog) (Rana nigromaculata).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Pelophylax.
OX   NCBI_TaxID=8409;
RN   [1]
RP   PROTEIN SEQUENCE.
RC   TISSUE=Skin;
RX   PubMed=5751736; DOI=10.1248/cpb.16.2088;
RA   Nakajima T.;
RT   "On the third active peptide on smooth muscle in the skin of Rana
RT   nigromaculata hallowell.";
RL   Chem. Pharm. Bull. 16:2088-2089(1968).
CC   -!- FUNCTION: Induces smooth muscle contraction. May target bradykinin
CC       receptors (BDKRB).
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- TISSUE SPECIFICITY: Expressed by the skin glands.
CC   -!- SIMILARITY: Belongs to the bradykinin-related peptide family.
CC       {ECO:0000305}.
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DR   PIR; A61362; A61362.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
DR   GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR   GO; GO:0042311; P:vasodilation; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Amphibian defense peptide; Direct protein sequencing;
KW   G-protein coupled receptor impairing toxin; Secreted; Toxin; Vasoactive;
KW   Vasodilator.
FT   PEPTIDE         1..14
FT                   /note="Bradykinin-like peptide 3"
FT                   /id="PRO_0000043525"
SQ   SEQUENCE   14 AA;  1486 MW;  33344EB3978393D7 CRC64;
     RPPGFSPFRV APAS