ID   BRK3_PITNO              Reviewed;           6 AA.
AC   P86428;
DT   09-FEB-2010, integrated into UniProtKB/Swiss-Prot.
DT   09-FEB-2010, sequence version 1.
DT   26-FEB-2020, entry version 14.
DE   RecName: Full=Bradykinin-related peptide Pnor-3 {ECO:0000303|Ref.1};
OS   Pithecopus nordestinus (Northeastern Brazilian leaf frog) (Phyllomedusa
OS   nordestina).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Neobatrachia; Hyloidea; Hylidae; Phyllomedusinae;
OC   Pithecopus.
OX   NCBI_TaxID=2034992;
RN   [1] {ECO:0000305}
RP   PROTEIN SEQUENCE, FUNCTION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, MASS
RP   SPECTROMETRY, AND AMIDATION AT LEU-6.
RC   TISSUE=Skin secretion {ECO:0000269|Ref.1};
RA   Conceicao K., Bruni F.M., Sciano J.M., Konno K., Melo R.L.,
RA   Antoniazzi M.M., Jared C., Lopes-Ferreira M., Pimenta D.C.;
RT   "Identification of bradykinin-related peptides from Phyllomedusa nordestina
RT   skin secretion using electrospray ionization tandem mass spectrometry after
RT   a single-step liquid chromatography.";
RL   J. Venom. Anim. Toxins Incl. Trop. Dis. 15:633-652(2009).
CC   -!- FUNCTION: Vasodilator. May target bradykinin receptors (BDKRB).
CC       {ECO:0000269|Ref.1}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|Ref.1}.
CC   -!- TISSUE SPECIFICITY: Expressed by the skin glands. {ECO:0000269|Ref.1}.
CC   -!- MASS SPECTROMETRY: Mass=811.41; Method=MALDI;
CC       Evidence={ECO:0000269|Ref.1};
CC   -!- SIMILARITY: Belongs to the bradykinin-related peptide family.
CC       {ECO:0000305}.
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DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
DR   GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR   GO; GO:0042311; P:vasodilation; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Amidation; Amphibian defense peptide; Bradykinin receptor impairing toxin;
KW   Direct protein sequencing; G-protein coupled receptor impairing toxin;
KW   Secreted; Toxin; Vasoactive; Vasodilator.
FT   PEPTIDE         1..6
FT                   /note="Bradykinin-related peptide Pnor-3"
FT                   /evidence="ECO:0000269|Ref.1"
FT                   /id="PRO_0000391417"
FT   MOD_RES         6
FT                   /note="Leucine amide"
FT                   /evidence="ECO:0000269|Ref.1"
SQ   SEQUENCE   6 AA;  812 MW;  6734137737635000 CRC64;
     KPLWRL