ID   BRK3_TRASC              Reviewed;           9 AA.
AC   P84497;
DT   25-JUL-2006, integrated into UniProtKB/Swiss-Prot.
DT   29-MAR-2005, sequence version 1.
DT   29-SEP-2021, entry version 30.
DE   RecName: Full=[Thr6]-bradykinin;
OS   Trachemys scripta (Red-eared slider turtle) (Pseudemys scripta).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira;
OC   Testudinoidea; Emydidae; Trachemys.
OX   NCBI_TaxID=34903;
RN   [1]
RP   PROTEIN SEQUENCE, SYNTHESIS, AND FUNCTION.
RX   PubMed=2298179; DOI=10.1210/endo-126-2-985;
RA   Conlon J.M., Hicks J.W., Smith D.D.;
RT   "Isolation and biological activity of a novel kinin ([Thr(6)]bradykinin)
RT   from the turtle, Pseudemys scripta.";
RL   Endocrinology 126:985-991(1990).
CC   -!- FUNCTION: Vasodilator. Increases aortic blood flow but, unlike
CC       bradykinin in mammalian systems, does not lower blood pressure in the
CC       turtle. May target bradykinin receptors (BDKRB).
CC       {ECO:0000269|PubMed:2298179}.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- SIMILARITY: Belongs to the bradykinin-related peptide family.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   PIR; A60579; A60579.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
DR   GO; GO:0042311; P:vasodilation; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; G-protein coupled receptor impairing toxin;
KW   Secreted; Toxin; Vasoactive; Vasodilator.
FT   PEPTIDE         1..9
FT                   /note="[Thr6]-bradykinin"
FT                   /id="PRO_0000247816"
SQ   SEQUENCE   9 AA;  1074 MW;  3393D771A9C86777 CRC64;
     RPPGFTPFR