ID   BRK_PARID               Reviewed;          13 AA.
AC   P42717;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   03-AUG-2022, entry version 62.
DE   RecName: Full=Waspkinin {ECO:0000303|Ref.1};
DE   AltName: Full=Bradykinin-related peptide {ECO:0000305};
OS   Parapolybia indica (Lesser paper wasp).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Vespoidea;
OC   Vespidae; Polistinae; Ropalidiini; Parapolybia.
OX   NCBI_TaxID=31921;
RN   [1]
RP   PROTEIN SEQUENCE, SUBCELLULAR LOCATION, AND PYROGLUTAMATE FORMATION AT
RP   GLN-1.
RC   TISSUE=Venom;
RA   Toki T., Yasuhara T., Nakajima T.;
RT   "Isolation and sequential analysis of peptides on the venom sac of
RT   Parapolybia indica.";
RL   Eisei Dobutsu 39:105-111(1988).
CC   -!- FUNCTION: Induces smooth muscle contraction. May target bradykinin
CC       receptors (BDKRB). May cause hypotension. {ECO:0000269|Ref.1}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|Ref.1}.
CC   -!- TISSUE SPECIFICITY: Expressed by the venom gland. {ECO:0000305|Ref.1}.
CC   -!- SIMILARITY: Belongs to the bradykinin-related peptide family.
CC       {ECO:0000305}.
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DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005179; F:hormone activity; IEA:InterPro.
DR   GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
DR   GO; GO:0006952; P:defense response; IEA:InterPro.
DR   GO; GO:0008217; P:regulation of blood pressure; IEA:UniProtKB-KW.
DR   GO; GO:0042311; P:vasodilation; IEA:UniProtKB-KW.
DR   InterPro; IPR009608; Bradykinin.
DR   Pfam; PF06753; Bradykinin; 1.
PE   1: Evidence at protein level;
KW   Bradykinin receptor impairing toxin; Direct protein sequencing;
KW   G-protein coupled receptor impairing toxin; Hypotensive agent;
KW   Pyrrolidone carboxylic acid; Secreted; Toxin; Vasoactive; Vasodilator.
FT   PEPTIDE         1..13
FT                   /note="Waspkinin"
FT                   /evidence="ECO:0000269|Ref.1"
FT                   /id="PRO_0000043516"
FT   MOD_RES         1
FT                   /note="Pyrrolidone carboxylic acid"
FT                   /evidence="ECO:0000269|Ref.1"
SQ   SEQUENCE   13 AA;  1573 MW;  2673CB3D83ECC867 CRC64;
     QZKRPPGFSP FRK