ID   BRK_VESXA               Reviewed;          12 AA.
AC   Q7M3T2;
DT   10-MAY-2004, integrated into UniProtKB/Swiss-Prot.
DT   15-DEC-2003, sequence version 1.
DT   29-SEP-2021, entry version 42.
DE   RecName: Full=Vespakinin-X {ECO:0000303|PubMed:264186};
DE   AltName: Full=Bradykinin-related peptide {ECO:0000305};
OS   Vespa xanthoptera (Japanese yellow hornet) (Vespa simillima xanthoptera).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Vespoidea;
OC   Vespidae; Vespinae; Vespa.
OX   NCBI_TaxID=7448;
RN   [1]
RP   PROTEIN SEQUENCE, AND SUBCELLULAR LOCATION.
RC   TISSUE=Venom;
RX   PubMed=264186; DOI=10.1248/cpb.25.936;
RA   Yasuhara T., Yoshida H., Nakajima T.;
RT   "Chemical investigation of the hornet (Vespa xanthoptera Cameron) venom.
RT   The structure of a new bradykinin analogue vespakinin-X.";
RL   Chem. Pharm. Bull. 25:936-941(1977).
CC   -!- FUNCTION: Bradykinins are a potent but short-lived agent of arteriolar
CC       dilation and increased capillary permeability (By similarity). May
CC       target bradykinin receptors (BDKRB). May cause hypotension.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:264186}.
CC   -!- TISSUE SPECIFICITY: Expressed by the venom gland.
CC       {ECO:0000305|PubMed:264186}.
CC   -!- SIMILARITY: Belongs to the bradykinin-related peptide family.
CC       {ECO:0000305}.
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DR   PIR; A61359; A61359.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
DR   GO; GO:0008217; P:regulation of blood pressure; IEA:UniProtKB-KW.
DR   GO; GO:0042311; P:vasodilation; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Bradykinin receptor impairing toxin; Direct protein sequencing;
KW   G-protein coupled receptor impairing toxin; Hypotensive agent; Secreted;
KW   Toxin; Vasoactive; Vasodilator.
FT   PEPTIDE         1..12
FT                   /note="Vespakinin-X"
FT                   /evidence="ECO:0000269|PubMed:264186"
FT                   /id="PRO_0000043518"
SQ   SEQUENCE   12 AA;  1344 MW;  2C9513C3D275B9C8 CRC64;
     ARPPGFSPFR IV