ID   BRLF1_EHV2              Reviewed;         682 AA.
AC   Q66652;
DT   08-MAR-2011, integrated into UniProtKB/Swiss-Prot.
DT   11-NOV-2015, sequence version 2.
DT   02-JUN-2021, entry version 56.
DE   RecName: Full=Putative transcription activator BRLF1 homolog;
GN   Name=50;
OS   Equine herpesvirus 2 (strain 86/87) (EHV-2).
OC   Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC   Herpesvirales; Herpesviridae; Gammaherpesvirinae; Percavirus.
OX   NCBI_TaxID=82831;
OH   NCBI_TaxID=9796; Equus caballus (Horse).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=7783207; DOI=10.1006/jmbi.1995.0314;
RA   Telford E.A.R., Watson M.S., Aird H.C., Perry J., Davison A.J.;
RT   "The DNA sequence of equine herpesvirus 2.";
RL   J. Mol. Biol. 249:520-528(1995).
RN   [2]
RP   SEQUENCE REVISION.
RA   Davison A.J.;
RL   Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Transcription activation. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the herpesviridae TAF50 family. {ECO:0000305}.
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DR   EMBL; U20824; AAC13838.2; -; Genomic_DNA.
DR   PIR; S55645; S55645.
DR   RefSeq; NP_042647.2; NC_001650.2.
DR   PRIDE; Q66652; -.
DR   GeneID; 1461040; -.
DR   KEGG; vg:1461040; -.
DR   Proteomes; UP000007083; Genome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   InterPro; IPR004998; Herpes_TAF50.
DR   Pfam; PF03326; Herpes_TAF50; 1.
PE   3: Inferred from homology;
KW   Activator; DNA-binding; Early protein; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..682
FT                   /note="Putative transcription activator BRLF1 homolog"
FT                   /id="PRO_0000406052"
FT   REGION          396..470
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          558..667
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        396..417
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        431..449
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        451..470
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        558..593
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        602..635
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        636..667
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   682 AA;  76570 MW;  0DE309BE785D532E CRC64;
     MEPKDFQPEI KPPKPFCIEQ FVGCSKEFKE KTLRLITLYH ECLINARGGD DFMRYMYDVC
     LSLEQEMRQY NALAGFLLEC NLFNLWNLFR NYKNKQSAES ANTNPCALMA QQFLKFHTER
     LLVCTDRFFS TGCCSQINMP YDLCQHVFKF QQDLRKRCIA SWKTLSGGRR AFMTVVQDIF
     TCFTTLRANE LITPRQQAFF KLSYPPCRVQ NVINILNVVH TQGIKDLKSL NMQKIKKRTP
     HAGIFSASGQ PLFPIPEALL VDFNGEGIIR SDIADVSPFL QNPEEFLATD FFTYIKRFQG
     VGVQIRDPEP RYQPASQQPQ QALRPQQQVL QQATAYPASV QAGGFAIQTE SPMEGTSAQY
     FLAAQQHGVV GLFPSTATLV PIAGSTGVTE VVSYGHNSTS PVSTFSAPST SVTEADHQTQ
     PRRSRKATAK RKHQQVQDGN EDEGPQRHPQ AHSRQFFQGA ASHQTAQPAQ VLQQSVIHGT
     QGALYFMGPA QQIPGDHSQI PVISNAMLQS VLQQQGGSGA AIYDLSQLQP CVVPVQQQAA
     QEVAVPTAVI HYQPAMQPQP QPYQQQQFLQ PQQQAQTPSP QMQQRQLTPQ SSPEPADEEE
     EGPLNLTTRT EDHEILEEIL SNLYPEERRQ QEQQHQQGEE AAPASPSQHE EQAGPSNQSG
     ETSQELDIFS LHNLHLRKSL FE