ID   BRM1L_XENLA             Reviewed;         322 AA.
AC   Q6AZT4;
DT   02-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT   13-SEP-2004, sequence version 1.
DT   03-AUG-2022, entry version 50.
DE   RecName: Full=Breast cancer metastasis-suppressor 1-like protein;
GN   Name=brms1l;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in the histone deacetylase (HDAC1)-dependent
CC       transcriptional repression activity. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the BRMS1 family. {ECO:0000305}.
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DR   EMBL; BC077352; AAH77352.1; -; mRNA.
DR   RefSeq; NP_001086722.1; NM_001093253.1.
DR   AlphaFoldDB; Q6AZT4; -.
DR   SMR; Q6AZT4; -.
DR   DNASU; 446557; -.
DR   GeneID; 446557; -.
DR   KEGG; xla:446557; -.
DR   CTD; 446557; -.
DR   Xenbase; XB-GENE-1002977; brms1l.L.
DR   OMA; ICIDRKD; -.
DR   OrthoDB; 1456563at2759; -.
DR   Proteomes; UP000186698; Chromosome 8L.
DR   Bgee; 446557; Expressed in egg cell and 19 other tissues.
DR   GO; GO:0005654; C:nucleoplasm; IEA:UniProt.
DR   InterPro; IPR013907; Sds3.
DR   PANTHER; PTHR21964; PTHR21964; 1.
DR   Pfam; PF08598; Sds3; 1.
DR   SMART; SM01401; Sds3; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; Nucleus; Reference proteome; Repressor; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..322
FT                   /note="Breast cancer metastasis-suppressor 1-like protein"
FT                   /id="PRO_0000305313"
FT   REGION          1..56
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          50..99
FT                   /evidence="ECO:0000255"
FT   COILED          147..178
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        1..20
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        22..48
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   322 AA;  37600 MW;  E90D49EA84CF9DE2 CRC64;
     MPVHSREKKE SNHNDMEVDY PENEGSSSEE DDSDSSSGSE EGDSSEMDDE DCERRRMECL
     DEMSTLEKQF TDLKDQLYKE RLSQVDAKLQ EVKADQAQEY LEPLANLQEN MQIRTKVAGI
     YRELCLESVK NKHDCEIQAA RQHCESEKLL LYDTVQSELE EKIRRLEEDR HSIDITSELW
     NDELQSRRKR KDPFSPDKKK KPVVVSGPYI VYMLQDLDIL EDWTTIRKAM ASFGPHRVKP
     EVTVKIEKHQ HSARSEEGRL HYDGEWYGRG QTICIDKKDE FPTSAVITTI NSDEVWFKRQ
     DGSKSKLYIS QLQKGKYSIK HI