BRNQL_STAA3
ID BRNQL_STAA3 Reviewed; 447 AA.
AC Q2FH31;
DT 10-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT 21-MAR-2006, sequence version 1.
DT 25-MAY-2022, entry version 84.
DE RecName: Full=Putative branched-chain amino acid carrier protein SAUSA300_1300;
GN OrderedLocusNames=SAUSA300_1300;
OS Staphylococcus aureus (strain USA300).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC Staphylococcus.
OX NCBI_TaxID=367830;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=USA300;
RX PubMed=16517273; DOI=10.1016/s0140-6736(06)68231-7;
RA Diep B.A., Gill S.R., Chang R.F., Phan T.H., Chen J.H., Davidson M.G.,
RA Lin F., Lin J., Carleton H.A., Mongodin E.F., Sensabaugh G.F.,
RA Perdreau-Remington F.;
RT "Complete genome sequence of USA300, an epidemic clone of community-
RT acquired meticillin-resistant Staphylococcus aureus.";
RL Lancet 367:731-739(2006).
CC -!- FUNCTION: Component of the transport system for branched-chain amino
CC acids (leucine, isoleucine and valine), which is coupled to a proton
CC motive force (Potential). Contributes to NaCl tolerance (By
CC similarity). {ECO:0000250, ECO:0000305}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the branched chain amino acid transporter
CC family. {ECO:0000305}.
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DR EMBL; CP000255; ABD22732.1; -; Genomic_DNA.
DR RefSeq; WP_001039275.1; NZ_CP027476.1.
DR AlphaFoldDB; Q2FH31; -.
DR EnsemblBacteria; ABD22732; ABD22732; SAUSA300_1300.
DR KEGG; saa:SAUSA300_1300; -.
DR HOGENOM; CLU_036807_0_1_9; -.
DR OMA; IWPAGPI; -.
DR Proteomes; UP000001939; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015658; F:branched-chain amino acid transmembrane transporter activity; IEA:InterPro.
DR InterPro; IPR004685; Brnchd-chn_aa_trnsp_Livcs.
DR PANTHER; PTHR30588; PTHR30588; 1.
DR Pfam; PF05525; Branch_AA_trans; 1.
DR TIGRFAMs; TIGR00796; livcs; 1.
PE 3: Inferred from homology;
KW Amino-acid transport; Cell membrane; Membrane; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..447
FT /note="Putative branched-chain amino acid carrier protein
FT SAUSA300_1300"
FT /id="PRO_0000294019"
FT TRANSMEM 6..26
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 40..60
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 74..94
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 114..134
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 143..163
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 193..213
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 229..249
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 290..310
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 326..346
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 350..370
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 382..402
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 417..437
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 447 AA; 48815 MW; 2B7384DF8C6B2745 CRC64;
MNKNTWVIGF TLFAMFFGAG NLIFPPNLGL DSGQFFWPAI LAFVLTGIGL PLLGVIVGAL
DKEGYIGALN KISPKFSILF LIIIYLTIGP LFAIPRTAST SFEMTITPII HSNSSIALFI
FTIIYFIVVL YICLNPSKLI DRIGSLLTPL LLITILAMII KGYLDFSGNS AGKGNEALYH
SNFSSFAEGF TQGYLTMDAI AAIAFSMIVV NAVKLTGITK TNQIFKQTLT AGLIAAVALI
FIYISLGYIG NHMPVSDMTL DQLKSKDRNI GTYLLTTMAS TGFGSFGKYL LGIIVALACL
TTACGLIVAV SEYFHRIVPK VSYKAFVLVF ILMSFIIANQ GLNAVISMSI PVLSIVYPVA
ITVVLLILIA KFIPTKRISQ QIPVIIVFIL SIFSVISKLG WLKINFIESL PLRAYSLEWF
PVAIIATILG YLVGIFVKQD PIKYQQE
