ID   BRNQL_STAAC             Reviewed;         447 AA.
AC   Q5HG12;
DT   10-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT   15-FEB-2005, sequence version 1.
DT   25-MAY-2022, entry version 96.
DE   RecName: Full=Putative branched-chain amino acid carrier protein SACOL1443;
GN   OrderedLocusNames=SACOL1443;
OS   Staphylococcus aureus (strain COL).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=93062;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=COL;
RX   PubMed=15774886; DOI=10.1128/jb.187.7.2426-2438.2005;
RA   Gill S.R., Fouts D.E., Archer G.L., Mongodin E.F., DeBoy R.T., Ravel J.,
RA   Paulsen I.T., Kolonay J.F., Brinkac L.M., Beanan M.J., Dodson R.J.,
RA   Daugherty S.C., Madupu R., Angiuoli S.V., Durkin A.S., Haft D.H.,
RA   Vamathevan J.J., Khouri H., Utterback T.R., Lee C., Dimitrov G., Jiang L.,
RA   Qin H., Weidman J., Tran K., Kang K.H., Hance I.R., Nelson K.E.,
RA   Fraser C.M.;
RT   "Insights on evolution of virulence and resistance from the complete genome
RT   analysis of an early methicillin-resistant Staphylococcus aureus strain and
RT   a biofilm-producing methicillin-resistant Staphylococcus epidermidis
RT   strain.";
RL   J. Bacteriol. 187:2426-2438(2005).
CC   -!- FUNCTION: Component of the transport system for branched-chain amino
CC       acids (leucine, isoleucine and valine), which is coupled to a proton
CC       motive force (Potential). Contributes to NaCl tolerance (By
CC       similarity). {ECO:0000250, ECO:0000305}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the branched chain amino acid transporter
CC       family. {ECO:0000305}.
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DR   EMBL; CP000046; AAW38188.1; -; Genomic_DNA.
DR   RefSeq; WP_001039275.1; NC_002951.2.
DR   AlphaFoldDB; Q5HG12; -.
DR   EnsemblBacteria; AAW38188; AAW38188; SACOL1443.
DR   KEGG; sac:SACOL1443; -.
DR   HOGENOM; CLU_036807_0_1_9; -.
DR   OMA; IWPAGPI; -.
DR   Proteomes; UP000000530; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015658; F:branched-chain amino acid transmembrane transporter activity; IEA:InterPro.
DR   InterPro; IPR004685; Brnchd-chn_aa_trnsp_Livcs.
DR   PANTHER; PTHR30588; PTHR30588; 1.
DR   Pfam; PF05525; Branch_AA_trans; 1.
DR   TIGRFAMs; TIGR00796; livcs; 1.
PE   3: Inferred from homology;
KW   Amino-acid transport; Cell membrane; Membrane; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..447
FT                   /note="Putative branched-chain amino acid carrier protein
FT                   SACOL1443"
FT                   /id="PRO_0000294012"
FT   TRANSMEM        6..26
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        40..60
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        74..94
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        114..134
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        143..163
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        193..213
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        229..249
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        290..310
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        326..346
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        350..370
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        382..402
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        417..437
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   447 AA;  48815 MW;  2B7384DF8C6B2745 CRC64;
     MNKNTWVIGF TLFAMFFGAG NLIFPPNLGL DSGQFFWPAI LAFVLTGIGL PLLGVIVGAL
     DKEGYIGALN KISPKFSILF LIIIYLTIGP LFAIPRTAST SFEMTITPII HSNSSIALFI
     FTIIYFIVVL YICLNPSKLI DRIGSLLTPL LLITILAMII KGYLDFSGNS AGKGNEALYH
     SNFSSFAEGF TQGYLTMDAI AAIAFSMIVV NAVKLTGITK TNQIFKQTLT AGLIAAVALI
     FIYISLGYIG NHMPVSDMTL DQLKSKDRNI GTYLLTTMAS TGFGSFGKYL LGIIVALACL
     TTACGLIVAV SEYFHRIVPK VSYKAFVLVF ILMSFIIANQ GLNAVISMSI PVLSIVYPVA
     ITVVLLILIA KFIPTKRISQ QIPVIIVFIL SIFSVISKLG WLKINFIESL PLRAYSLEWF
     PVAIIATILG YLVGIFVKQD PIKYQQE