ID   BRNQ_CORGL              Reviewed;         426 AA.
AC   O06754;
DT   15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT   11-JUL-2002, sequence version 2.
DT   03-AUG-2022, entry version 119.
DE   RecName: Full=Branched-chain amino acid transport system carrier protein;
DE   AltName: Full=Branched-chain amino acid uptake carrier;
GN   Name=brnQ; OrderedLocusNames=Cgl2310, cg2537;
OS   Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 /
OS   JCM 1318 / LMG 3730 / NCIMB 10025).
OC   Bacteria; Actinobacteria; Corynebacteriales; Corynebacteriaceae;
OC   Corynebacterium.
OX   NCBI_TaxID=196627;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB
RC   10025;
RA   Tauch A., Hermann T., Burkovski A., Kraemer R., Kalinowski J., Puehler A.;
RL   Submitted (MAR-1992) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB
RC   10025;
RX   PubMed=12743753; DOI=10.1007/s00253-003-1328-1;
RA   Ikeda M., Nakagawa S.;
RT   "The Corynebacterium glutamicum genome: features and impacts on
RT   biotechnological processes.";
RL   Appl. Microbiol. Biotechnol. 62:99-109(2003).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB
RC   10025;
RX   PubMed=12948626; DOI=10.1016/s0168-1656(03)00154-8;
RA   Kalinowski J., Bathe B., Bartels D., Bischoff N., Bott M., Burkovski A.,
RA   Dusch N., Eggeling L., Eikmanns B.J., Gaigalat L., Goesmann A.,
RA   Hartmann M., Huthmacher K., Kraemer R., Linke B., McHardy A.C., Meyer F.,
RA   Moeckel B., Pfefferle W., Puehler A., Rey D.A., Rueckert C., Rupp O.,
RA   Sahm H., Wendisch V.F., Wiegraebe I., Tauch A.;
RT   "The complete Corynebacterium glutamicum ATCC 13032 genome sequence and its
RT   impact on the production of L-aspartate-derived amino acids and vitamins.";
RL   J. Biotechnol. 104:5-25(2003).
CC   -!- FUNCTION: Component of the transport system for branched-chain amino
CC       acids (leucine, isoleucine and valine) Which is coupled to a proton
CC       motive force. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the branched chain amino acid transporter
CC       family. {ECO:0000305}.
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DR   EMBL; M89931; AAC18909.1; -; Genomic_DNA.
DR   EMBL; BA000036; BAB99703.1; -; Genomic_DNA.
DR   EMBL; BX927154; CAF20652.1; -; Genomic_DNA.
DR   RefSeq; NP_601509.1; NC_003450.3.
DR   RefSeq; WP_011015030.1; NC_006958.1.
DR   AlphaFoldDB; O06754; -.
DR   STRING; 196627.cg2537; -.
DR   KEGG; cgb:cg2537; -.
DR   KEGG; cgl:Cgl2310; -.
DR   PATRIC; fig|196627.13.peg.2243; -.
DR   eggNOG; COG1114; Bacteria.
DR   HOGENOM; CLU_036807_0_1_11; -.
DR   OMA; IWPAGPI; -.
DR   Proteomes; UP000000582; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015658; F:branched-chain amino acid transmembrane transporter activity; IEA:InterPro.
DR   InterPro; IPR004685; Brnchd-chn_aa_trnsp_Livcs.
DR   PANTHER; PTHR30588; PTHR30588; 1.
DR   Pfam; PF05525; Branch_AA_trans; 1.
DR   TIGRFAMs; TIGR00796; livcs; 1.
PE   3: Inferred from homology;
KW   Amino-acid transport; Cell membrane; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..426
FT                   /note="Branched-chain amino acid transport system carrier
FT                   protein"
FT                   /id="PRO_0000099772"
FT   TRANSMEM        11..31
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        41..61
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        76..96
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        111..131
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        140..160
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        186..206
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        219..239
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        268..288
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        296..316
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        324..344
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        358..378
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        390..410
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   CONFLICT        163
FT                   /note="L -> M (in Ref. 1; AAC18909)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   426 AA;  44832 MW;  F6519D59A7E5861E CRC64;
     MSKKSVLITS LMLFSMFFGA GNLIFPPMLG LSAGTNYLPA ILGFLATSVL LPVLAIIAVV
     LSGENVKDMA SRGGKIFGLV FPIAAYLSIG AFYALPRTGA VSYSTAVGVD NALYSGLFNF
     VFFAVALALS WNPNGIADKL GKWLTPALLT LIVVLVVLSV AKLDGTPGEP SSAYAQQPAG
     AGLLEGYMTM DAIAALAFGI VVISAFKYQK VNKVRTATVV SAFIAGILLA LVYLGLGSIG
     QVVNGEFADG TAILNYAALS TMGQAGRIMF VAILILACMT TAVGLISATS EFFNSLLPGV
     KYHVWATVFA LISFGVATMG LDTVLAVAAP VISFIYPSAI TLVFLSLIEP LLFRLKWTYL
     FGIWTAVVWA LFMSIPALNP FIEWAPLHSM SLGWVVPVLV ASAIGLAIDW NKKGAQSVAK
     KESISV