ID   BRNQ_HAEIN              Reviewed;         436 AA.
AC   P71345;
DT   15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1997, sequence version 1.
DT   03-AUG-2022, entry version 112.
DE   RecName: Full=Branched-chain amino acid transport system carrier protein;
DE   AltName: Full=Branched-chain amino acid uptake carrier;
GN   Name=brnQ; OrderedLocusNames=HI_0226;
OS   Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=71421;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX   PubMed=7542800; DOI=10.1126/science.7542800;
RA   Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA   Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA   McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA   Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA   Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA   Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA   Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA   Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT   "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT   Rd.";
RL   Science 269:496-512(1995).
CC   -!- FUNCTION: Component of the transport system for branched-chain amino
CC       acids (leucine, isoleucine and valine) Which is coupled to a proton
CC       motive force. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the branched chain amino acid transporter
CC       family. {ECO:0000305}.
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DR   EMBL; L42023; AAC21896.1; -; Genomic_DNA.
DR   PIR; D64056; D64056.
DR   RefSeq; NP_438398.1; NC_000907.1.
DR   RefSeq; WP_005694065.1; NC_000907.1.
DR   AlphaFoldDB; P71345; -.
DR   STRING; 71421.HI_0226; -.
DR   EnsemblBacteria; AAC21896; AAC21896; HI_0226.
DR   KEGG; hin:HI_0226; -.
DR   PATRIC; fig|71421.8.peg.240; -.
DR   eggNOG; COG1114; Bacteria.
DR   HOGENOM; CLU_036807_0_1_6; -.
DR   OMA; AFAFSYH; -.
DR   PhylomeDB; P71345; -.
DR   BioCyc; HINF71421:G1GJ1-243-MON; -.
DR   Proteomes; UP000000579; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0015188; F:L-isoleucine transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0015190; F:L-leucine transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0005304; F:L-valine transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0015818; P:isoleucine transport; IBA:GO_Central.
DR   GO; GO:0015820; P:leucine transport; IBA:GO_Central.
DR   GO; GO:0015829; P:valine transport; IBA:GO_Central.
DR   InterPro; IPR004685; Brnchd-chn_aa_trnsp_Livcs.
DR   PANTHER; PTHR30588; PTHR30588; 1.
DR   Pfam; PF05525; Branch_AA_trans; 1.
DR   TIGRFAMs; TIGR00796; livcs; 1.
PE   3: Inferred from homology;
KW   Amino-acid transport; Cell inner membrane; Cell membrane; Membrane;
KW   Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..436
FT                   /note="Branched-chain amino acid transport system carrier
FT                   protein"
FT                   /id="PRO_0000099769"
FT   TRANSMEM        7..27
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        43..63
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        76..96
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        122..142
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        148..168
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        185..205
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        228..248
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        277..297
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        314..334
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        339..359
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        411..431
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   436 AA;  47039 MW;  FA37EDF6C2193FDF CRC64;
     MFSRKDIIVL GMMIFALFLG AGNIIFPPME GFSSGQHWTS ASLGFVLTGV LMPFITLVVV
     AILGRGEELT KDLPKWAGTG FLVILYLTIG STFAMPRITN VAYEMAWLPL GLTENNANVR
     FVFSLIFNLI AMGFMISPNT IISSVGKFMT PALLVLLIAV AITVFISPLS EIQAPSNAYE
     NSHSLLIGLT SGYQTMDVLA AIAFGGIVAR ALSAKNVTKT KDIVKYTISA GFVSVILLAG
     LYFSLFYLGA TSAAVAEGAT NGGQIFSRYV NVLFGSAGTW IMAGIIVLAS LTTLVGVTSA
     SADYFSKFSV RFSYPFWAAL FTAMTITVSQ YGLTDLLRIT IPALLLIYPV AIVLVLLQFL
     RKKLPSIKFT YNSTLLVTVC FSLCDSLNNV KMLPESINSL LKHFPLSSEG MAWLVPTLVM
     LVASIFIGKA LHKTHS