BRNQ_LACDL
ID BRNQ_LACDL Reviewed; 446 AA.
AC P54104;
DT 01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-1996, sequence version 1.
DT 03-AUG-2022, entry version 74.
DE RecName: Full=Branched-chain amino acid transport system carrier protein;
DE AltName: Full=Branched-chain amino acid uptake carrier;
GN Name=brnQ;
OS Lactobacillus delbrueckii subsp. lactis.
OC Bacteria; Firmicutes; Bacilli; Lactobacillales; Lactobacillaceae;
OC Lactobacillus.
OX NCBI_TaxID=29397;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=DSM 7290;
RX PubMed=8544834; DOI=10.1007/bf00418038;
RA Stucky K., Hagting A., Klein J.R., Matern H., Henrich B., Konings W.N.,
RA Plapp R.;
RT "Cloning and characterization of brnQ, a gene encoding a low-affinity,
RT branched-chain amino acid carrier in Lactobacillus delbruckii subsp. lactis
RT DSM7290.";
RL Mol. Gen. Genet. 249:682-690(1995).
CC -!- FUNCTION: Component of the transport system for branched-chain amino
CC acids (leucine, isoleucine and valine) Which is coupled to a proton
CC motive force.
CC -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC -!- SIMILARITY: Belongs to the branched chain amino acid transporter
CC family. {ECO:0000305}.
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DR EMBL; Z48676; CAA88595.1; -; Genomic_DNA.
DR PIR; S60180; S60180.
DR AlphaFoldDB; P54104; -.
DR TCDB; 2.A.26.1.3; the branched chain amino acid:cation symporter (livcs) family.
DR PRIDE; P54104; -.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015658; F:branched-chain amino acid transmembrane transporter activity; IEA:InterPro.
DR InterPro; IPR004685; Brnchd-chn_aa_trnsp_Livcs.
DR PANTHER; PTHR30588; PTHR30588; 1.
DR Pfam; PF05525; Branch_AA_trans; 1.
DR TIGRFAMs; TIGR00796; livcs; 1.
PE 3: Inferred from homology;
KW Amino-acid transport; Cell membrane; Membrane; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..446
FT /note="Branched-chain amino acid transport system carrier
FT protein"
FT /id="PRO_0000099773"
FT TRANSMEM 13..33
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 41..61
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 81..101
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 120..140
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 154..174
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 196..216
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 237..257
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 285..305
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 325..345
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 347..367
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 381..401
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 421..441
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 446 AA; 47869 MW; 6AA20B85DE0F9391 CRC64;
MKEKLTHAES LTISSMLFGL FFGAGNLIFP AYLGEASGAN LWISLLGFLI TGVGLPLLAI
ASLGMTRSEG LLDLSGRVSH KYSYFFTCLL YLTIGPFFAI PRSFTVPFET GISALLPSGM
AKSTGLFIFS LIFFAIMLFF SLRPGQIMDW IGKFLTPAFL LFFFFIMIMA LLHPLGNYHA
VKPVGEYASA PLISGVLAGY NTMDALAGLA FGIIVISSIR TFGVTKPEKV ASATLKTGVL
TCLLMAVIYA ITALVGAQSR TALGLAANGG EALSQIARHY FPGLGAVIFA LMIFVACLKT
AIGLITACSE TFAEMFPKTL SYNMWAIIFS LLAFGIANVG LTTIISFSLP VLMLLYPLAI
SLILLALTSK LFDFKQVDYQ IMTAVTFLCA LGDFFKALPA GMQVKAVTGL YGHVLPLYQD
GLGWLVPVTV IFAILAIKGV ISKKRA
