ID   BROX_CAEEL              Reviewed;         427 AA.
AC   Q22885;
DT   11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2003, sequence version 2.
DT   03-AUG-2022, entry version 103.
DE   RecName: Full=BRO1 domain-containing protein BROX homolog;
GN   ORFNames=B0507.2;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
CC   -!- SIMILARITY: Belongs to the BROX family. {ECO:0000305}.
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DR   EMBL; FO080216; CCD62069.1; -; Genomic_DNA.
DR   PIR; T25472; T25472.
DR   RefSeq; NP_505261.2; NM_072860.5.
DR   AlphaFoldDB; Q22885; -.
DR   SMR; Q22885; -.
DR   BioGRID; 44294; 3.
DR   STRING; 6239.B0507.2; -.
DR   EPD; Q22885; -.
DR   PaxDb; Q22885; -.
DR   PeptideAtlas; Q22885; -.
DR   EnsemblMetazoa; B0507.2.1; B0507.2.1; WBGene00015219.
DR   GeneID; 179255; -.
DR   UCSC; B0507.2; c. elegans.
DR   CTD; 179255; -.
DR   WormBase; B0507.2; CE32561; WBGene00015219; -.
DR   eggNOG; KOG2220; Eukaryota.
DR   GeneTree; ENSGT00390000006681; -.
DR   HOGENOM; CLU_056561_0_0_1; -.
DR   InParanoid; Q22885; -.
DR   OMA; HTCLRRA; -.
DR   OrthoDB; 614228at2759; -.
DR   PhylomeDB; Q22885; -.
DR   PRO; PR:Q22885; -.
DR   Proteomes; UP000001940; Chromosome V.
DR   Bgee; WBGene00015219; Expressed in pharyngeal muscle cell (C elegans) and 3 other tissues.
DR   Gene3D; 1.25.40.280; -; 1.
DR   InterPro; IPR004328; BRO1_dom.
DR   InterPro; IPR038499; BRO1_sf.
DR   InterPro; IPR038898; BROX.
DR   PANTHER; PTHR23032; PTHR23032; 1.
DR   Pfam; PF03097; BRO1; 1.
DR   SMART; SM01041; BRO1; 1.
DR   PROSITE; PS51180; BRO1; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..427
FT                   /note="BRO1 domain-containing protein BROX homolog"
FT                   /id="PRO_0000304618"
FT   DOMAIN          1..427
FT                   /note="BRO1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00526"
SQ   SEQUENCE   427 AA;  48299 MW;  E3B4D8A655B74B67 CRC64;
     MSHWFHRNPI KPTEFVKFDL KGVLTTDTCS KICGELRLRR DKLVSQFKNA SNDLEEVTKE
     FNEYLRLFAG FLIEIQSSMV ELENKDAGNK NSKLIPLIRF KWGNSMLPQA ATEVSDTWFE
     ALSMIQCMAM WLTKHAASMA GKDEVRESDA KECLQCLRQA GGMFQYVKDE SSRLSGANEV
     EGSDFDPKVM ETYILTATAE AQEVIVARAI EMKHDDGLIS SLAAVTASIF SKADQCLNNL
     PDESFARWRR YLQLKHHFYL AYAFAFLGQK QLSEDKCGEA VRACKQGIAE YGVAKEMAAM
     YATATGPGTR IKPEQHLFFR RIEPLLNRHL EKAERENGFI YHQKVPDEIP QLDVEATYGL
     AKLDSFTYPP PAESWNTAVY SAFDLSKANM PDFSKIKKSK SKLDPVHEEK IYQTEKDPSN
     SSGCVIA